Thiopurine methyltransferase biochemical genetics: Human lymphocyte activity

Biochemical Genetics

Volumn 20, Issue 7-8, 1982, Pages 637-658

  Van Loon, Jon A ^a   Weinshilboum, Richard M ^a  

^a MAYO CLINIC COLLEGE OF MEDICINE   (United States)

Author keywords

biochemical genetics; lymphocyte enzyme; methyltransferase; pharmacogenetics; thiopurine

Indexed keywords

DITHIOTHREITOL; ENZYME; GLUTATHIONE; LYMPHOCYTE ENZYME; MERCAPTOPURINE; RADIOISOTOPE; S ADENOSYLMETHIONINE; THIOPURINE METHYLTRANSFERASE; TROMETAMOL;

ADENOSYLMETHIONINE C 14; BLOOD AND HEMOPOIETIC SYSTEM; ERYTHROCYTE; GENETIC POLYMORPHISM; HEREDITY; HUMAN; HUMAN CELL; KIDNEY; LYMPHATIC SYSTEM; LYMPHOCYTE; METHYLMERCAPTOPURINE; PHARMACOGENETICS; THIN LAYER CHROMATOGRAPHY; THROMBOCYTE;

ADULT; ALLELES; BLOOD PLATELETS; CELL SEPARATION; CYTOSOL; ERYTHROCYTES; GENOTYPE; HUMAN; LYMPHOCYTES; METHYLTRANSFERASES; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0019987157     PISSN: 00062928     EISSN: 15734927     Source Type: Journal    
DOI: 10.1007/BF00483962     Document Type: Article

References (22)

1. The effect of 6-mercaptopurine on the duration of steroid-induced remissions in acute leukemia: A model for evaluation of other potentially useful therapy
2. Separation of leukocytes from blood and bone marrow
3. Enzymatic methylation of foreign sulfhydryl compounds
4. Computer programmes for processing enzyme kinetic data
5. Human thiopurine methyltransferase (TPMT) biochemical genetics
6. Hepatotoxicity of mercaptopurine
7. The direct linear plot
8. Biochemistry and pharmacology of purine analogues
9. Protein carboxymethylation: Role in the regulation of cell functions
10. Thiol S-methylation in uremia: Erythrocyte enzyme activities and plasma inhibitors
11. Purification of lymphocytes and platelets by gradient centrifugation
12. Metabolism of thiopyrimidines and thiopurines
13. Catechol-0-methyltransferase biochemical genetics: Human lymphocyte enzyme
14. Rat thiopurine methyltransferase: Assay procedure, developmental changes and strain variation
15. “Methylator status” and assessment of variation in drug metabolism
16. Mercaptopurine pharmacogenetics: Monogenic inheritance of erythrocyte thiopurine methyltransferase activity
17. Human erythrocyte thiopurine methyltransferase: Radiochemical microassay and biochemical properties
18. Human erythrocyte thiol methyltransferase: Radiochemical microassay and biochemical properties
19. Statistical estimations in enzyme kinetics
20. Rat thiopurine methyltransferase: Regulation by testosterone
21. Biochemical genetics of human erythrocyte (RBC) thiopurine methyltransferase (TPMT): Correlation of immunoreactive protein with enzyme activity