Interaction between phenytoin and diazepam in mutant Han-Wistar rats with progressive spastic paresis

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 321, Issue 1, 1982, Pages 48-51

  Turski, Lechosław ^a   Schwarz, Michael ^a   Sontag, Karl Heinz ^a  

^a MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

Author keywords

Diazepam; Electromyogram; Mutant Han Wistar rats; Phenytoin

Indexed keywords

DIAZEPAM; PHENYTOIN; PICROTOXIN;

ANIMAL EXPERIMENT; CENTRAL NERVOUS SYSTEM; DRUG INTERACTION; ELECTROMYOGRAPHY; GASTROCNEMIUS MUSCLE; HEREDITY; MUSCLE; MUTANT; RAT; SPASTIC PARESIS;

ANIMAL; DIAZEPAM; DRUG INTERACTIONS; ELECTROMYOGRAPHY; FEMALE; MALE; MUSCLE SPASTICITY; MUSCLES; PARALYSIS; PHENYTOIN; PICROTOXIN; RATS; RATS, MUTANT STRAINS; TIME FACTORS;

EID: 0019975820     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/BF00586348     Document Type: Article

References (29)

1. The pharmacology of spasticity
2. Chlordiazepoxide selectively augments GABA action in spinal cord cell cultures
3. Molecular mechanisms in the receptor action of the benzodiazepines
4. Diphenylhydantoin potentiates the protective effect of diazepam against pentylenetetrazol but not against bicuculline and isoniazid-induced seizures in mice
5. Effect of combined treatment of diphenylhydantoin with diazepam on the susceptibility of mice to electroconvulsions
6. Effects of combined treatment with diphenylhydantoin and different benzodiazepines on pentylenetetrazol and bicuculline-induced seizures in mice
7. The effect of bicuculline upon synaptic inhibition in the cerebral and cerebellar cortices of the cat
8. Benzodiazepines: potentiation of a GABA inhibiting response in the dorsal raphe nucleus
9. Interaction of diphenylhydantoin and benzodiazepines in the CNS
10. Possible involvement of GABA in the central action of benzodiazepines
11. General pharmacology and neuropharmacology of benzodiazepine derivatives
12. Stimulation of benzodiazepine receptor binding by γ-aminobutyric acid
13. Dihydropicrotoxinin binding sites in mammalian brain: interaction with convulsant and depressant benzodiazepines
14. Benzodiazepine receptors: Cellular and behavioral characteristics
15. Enhancement of GABA-mediated postsynaptic inhibition in cultured mammalian spinal cord neurons: A common mode of anticonvulsant action
16. Evidence for an involvement of GABA in the mediation of the cerebellar cGMP decrease and the anticonvulsant action of diazepam
17. GABA-benzodiazepine-barbiturate receptor interactions
18. Convulsant and anticonvulsant drug binding sites related to GABA-regulated chloride ion channels
19. Effects of drugs on γ-aminobutyric acid receptors, uptake, release and synthesis in vitro
20. Some characteristics of mutant Han-Wistar rats which exhibit paresis and paralysis
21. Mutant spastic Han-Wistar rats: Biochemical abnormalities in their striata
22. Electromyographical and biochemical studies on mutant Han-Wistar rats with progressive spastic paresis
23. Spontaneous occurrence of spastic paresis in Han-Wistar rats
24. Modulation of benzodiazepine binding site sensitivity
25. Receptors for the age of anxiety: Pharmacology of the benzodiazepines
26. Benzodiazepine binding sites: Properties and modulation
27. Diphenylhydantoin enhancement of diazepam effects on locomotor activity in mice
28. Morphine-induced muscular rigidity in rats
29. The role of GABA metabolism in the convulsant and anticonvulsant actions of amino-oxyacetic acid