Intravenous and subcutaneous desferrioxamine therapy in children with severe iron overload

European Journal of Pediatrics

Volumn 137, Issue 3, 1981, Pages 285-290

  Janka, G E ^a   Mohring P ^a   Helmig, M ^a   Haas, R J ^a   Betke, K ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Desferrioxamine; Ferritin; Hemosiderosis; Liver storage iron; Thalassemia

Indexed keywords

DEFEROXAMINE; FERRITIN; IRON;

ANEMIA; BLOOD AND HEMOPOIETIC SYSTEM; BLOOD TRANSFUSION; HEMOSIDEROSIS; HEREDITY; INTRAVENOUS DRUG ADMINISTRATION; IRON LIVER LEVEL; LIVER; MAJOR CLINICAL STUDY; PRESCHOOL CHILD; PREVENTION; PROPHYLAXIS; SCHOOL CHILD; SUBCUTANEOUS DRUG ADMINISTRATION; THALASSEMIA; THERAPY;

ADOLESCENT; ANEMIA, APLASTIC; ANEMIA, SIDEROBLASTIC; BLOOD TRANSFUSION; CHILD; CHILD, PRESCHOOL; DEFEROXAMINE; HEMOSIDEROSIS; HUMANS; IRON; THALASSEMIA;

EID: 0019867789     PISSN: 03406199     EISSN: 14321076     Source Type: Journal    
DOI: 10.1007/BF00443259     Document Type: Article

References (18)

1. Clinical and laboratory studies on the action of desferrioxamine
2. Serum ferritin, liver iron stores and liver histology in children with thalassaemia
3. Editorial: Desferrioxamine and transfusional iron overload (1978). Lancet 1:479–480
4. Chelation therapy in β-thalassemia major. I. Intravenous and subcutaneous desferrioxamine
5. Mechanism of desferrioxamine-induced iron excretion in thalassemia
6. Effect of dose, time and ascorbate on iron excretion after subcutaneous desferrioxamine
7. Jacobs A, Miller F, Worwood M, Beamish MR, Wardrop CA (1972) Ferritin in the serum of normal subjects and patients with iron deficiency and iron overload. Br Med J: 206–208
8. Serum ferritin in children with thalassemia regularly transfused
9. A clinical evaluation of serum ferritin as an index of iron stores
10. Total management of thalassaemia major
11. Long-term desferrioxamine therapy in thalassemia
12. Reassessment of the use of desferrioxamine B in iron overload
13. Continuous subcutaneous administration of desferrioxamine in patients with iron-overload
14. New approaches to the transfusion management of thalassemia
15. Long-term administration of desferrioxamine in thalassaemia major
16. Studies in desferrioxamine and ferrioxamine metabolism in normal and iron-loaded subjects
17. The effect of ascorbic acid deficiency on desferrioxamine-induced iron excretion
18. Cooley anemia: high transfusion regimen and chelation therapy, results, and per-spective