Effect of Plasminogen Activator (Urokinase), Piasmin, and Thrombin on Glycoprotein and Collagenous Components of Basement Membrane

Cancer Research

Volumn 41, Issue , 1981, Pages 4629-4636

  Liotta, L A ^a   Brundage, R ^a   Siegal, G P ^a   Goldfarb, R H ^a   Terranova, V ^a   Garbisa, S ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

APROTININ; CHYMOSTATIN; COLLAGEN; FIBRONECTIN; GLYCOPROTEIN; HIRUDIN; LAMININ C 14; LEUPEPTIN; PLASMIN; PLASMINOGEN; PLASMINOGEN ACTIVATOR; THROMBIN; UNCLASSIFIED DRUG; UROKINASE;

ANIMAL EXPERIMENT; ARTICLE; BASEMENT MEMBRANE; FIBRINOLYSIS; MAMMAL; METASTASIS;

AMNION; BASEMENT MEMBRANE; COLLAGEN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLYCOPROTEINS; HUMANS; IMMUNOLOGIC TECHNIQUES; LAMININ; MEMBRANE PROTEINS; PLASMIN; PLASMINOGEN ACTIVATORS; THROMBIN;

EID: 0019850184     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Astedt, B., and Holmberg, L. Immunological identity of urokinase and ovarian carcinoma plasminogen activator released in tissue culture. Nature (Lond.), 267: 595–597, 1976.
2. Babai, F. Etude ultrastructural sur la pathogénie de I'invasion du muscle strié par des tumeurs transplantables. J. Ultrastruct. Res., 56: 287–303, 1976.
3. Bornstein, P. and Sage, H. Structurally distinct collagen types. Annu. Rev. Biochem., 49: 957–1003, 1980.
4. Burgeson, R. E. El Adil, F. A., Kaitila, I. I., and Hollister, D. W. Fetal membrane collagens: Identification of two new collagen alpha chains. Proc. Natl. Acad. Sci. U. S. A. 73: 2579–2580, 1976.
5. Christman. J. K., Silverstein, S. C., and Acs, G. Plasminogen activators. In: A. J. Barrett (ed.), Proteinases in Mammalian Cells and Tissues, pp. 91-149. Amsterdam: Elsevier/North-Holland Biomedical Press, 1977.
6. Fenton, J. W., Fasco, M. J., Stackrow, A. B., Aronson, D. L., Young, A. M., and Finlayson, J. W. Human thrombins: production, evaluation, and properties of α-thrombin. J. Biol. Chem., 252: 3587–3598, 1977.
7. Fidler, I. J. Gersten, D. M., and Hart, I. R. The Biology of cancer invasion and metastasis. Adv. Cancer Res., 28: 149–250, 1978.
8. Furie, M. B., and Rifkin, D. B. Proteolytically derived fragments of human plasma fibronectin and their localization within the intact molecule. J. Biol. Chem., 255: 3134–3140, 1980.
9. Goldfarb, R. H., and Quigley, J. P. Synergistic effect of tumor virus transformation and tumor promoter treatment on the production of plasminogen activator by chick embryo fibroblasts. Cancer Res., 38: 4601-4609, 1978.
10. Goldfarb, R. H., and Quigley, J. P. Purification of plasminogen activator from Rous sarcoma virus transformed chick embryo fibroblasts treated with the tumor promoter phorbol-12-myristate-13-acetate. Biochemistry, 19: 5463-5471, 1980.
11. Hynes, R. P., Wyke, J. A., Bye, J. M., Humphryes, K. C., and Pearlstein, E. S. Are Proteases involved in altering surface proteins during transformation. Cold Spring Harbor Conf. Cell Proliferation, 2: 931–944, 1975.
12. Jones. P. A., and DeClerk, Y. A. Destruction of extracellular matrices containing glycoproteins, elastin, and collagen by metastatic human tumor cells. Cancer Res., 40: 3222–3227, 1980.
13. Kefalides, N. A. (ed.). Biology and Chemistry of Basement Membranes. New York: Academic Press, Inc., 1978.
14. Kresina, T. F., and Miller. E. J. Isolation and characterization of basement membrane collagen from human placental tissue. Evidence for the presence of two genetically distinct collagen chains. Biochemistry, 18: 3089–3097, 1979.
15. Laemmli, U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond.), 227: 680–685, 1970.
16. Liotta, L. A., Abe, S., Gehron-Robey, P., and Martin, G. R. Preferential digestion of basement membrane collagen by an enzyme derived from a metastatic murine tumor. Proc. Natl. Acad. Sci. U. S. A., 76: 2268–2272, 1979.
17. Liotta. L. A. Gattozzi, C. Kleinerman, J. and Saidel, G. Reduction of tumor cell entry into vessels by BCG-activated macrophages. Br. J. Cancer, 36: 639–641, 1977.
18. Liotta. L. A., Kleinerman. J., Catanzaro. P., and Rynbrandt. D. Degradation of basement membrane by murine tumor cells. J. Natl. Cancer Inst., 58: 1427–1431, 1977.
19. Liotta, L. A., Lanzer, W. L., and Garbisa, S. Identification of a type V collagenolytic enzyme. Biochem. Biophys. Res. Commun., 98: 184–190, 1981.
20. Liotta, L. A., Lee, C. and Morakis, D. J. New method for preparing whole intact surfaces of human basement membrane for tumor invasion studies. Cancer Lett., 11: 141–152. 1980.
21. Liotta, L. A., Tryggvason, K., Garbisa, S., Gehron-Robey, P., and Abe, S. Partial purification and characterization of a neutral protease which cleaves type IV collagen. Biochemistry, 20: 100–104, 1981.
22. Liotta, L. A., Tryggvason, K., Garbisa, S., Hart, I., Foltz, C. M., and Shafie, S. Metastatic potential correlates with enzymatic degradation of basement membrane collagen. Nature (Lond.), 284: 67–68, 1980.
23. Madri, J. A., and Furthmayr, H., Isolation and tissue localization of type AB2 collagen from normal lung parenchyma. Am. J. Pathol. 94:323-331. 1980.
24. Mainardi, C. L., Dixit, S. N., and Kang, A. H. Degradation of (Type IV) basement membrane collagen by a proteinase isolated from human polymorphonuclear leucocyte granules. J. Biol. Chem., 255:5435-5441, 1980.
25. Marchesi, V. T. Ultrastructural aspects of acute inflammation. Pathol. Annu., Vol. 5, 343–353, 1970.
26. Markus, G., Takita, H., Camiolo, S. M., Corasanti, J. G., Evers, J. L., and Hobika, G. H. Content and characterization of plasminogen activators in human lung tumors and normal lung tissue. Cancer Res., 40: 841–848, 1980.
27. Martinez-Hernandez, A., Fink, L. M., and Pierce G. B. Removal of basement membrane in the involuting breast. Lab. Invest., 34. 455–462. 1976.
28. Minor, R. R., Clark, C. C., Strause, E. L., Koszalka, T. R., Brent, R. L., and Kefalides, N. A. Basement membrane procollagen is not converted to collagen in organ cultures of parietal yolk sac endoderm. J. Biol. Chem., 257: 1789–1794, 1976.
29. Mosesson, M. W. The preparation of human fibrinogen free of plasminogen. Biochim. Biophys. Acta, 57: 204–213, 1962.
30. Mosesson, M. W., and Amrani, D.L. The structure and biologic activities of plasma fibronectin. Blood, 56: 145–158, 1980.
31. Mosesson, M. W. and Finlayson, J. S. The search for the structure of fibrinogen. In: T. H. Spaet (ed.). Progress in Hemostasis and Thrombosis. Vol. 3, pp. 61–107. New York: Grune & Stratton, 1976.
32. Murano, G., Aronson, D., Williams, L., and Brown, L. The inhibition of high and low molecular weight urokinase in plasma. Blood. 55: 430–436, 1980.
33. Murphy, M. E., and Johnson, P. C. Possible contribution of basement membrane to the structural rigidity of blood capillaries. Microvasc. Res., 9: 242–245, 1975.
34. Paranjpe, M., Engel. E., Young, N. and Liotta, L. A. Activation of human breast carcinoma collagenase through plasminogen activator. Life Sci., 26: 1223–1231, 1980.
35. Quigley, J. P., Martin, B. M., Goldfarb. R. H., Scheiner, C. J., and Muller. W. D. Involvement of serine proteases in growth control and malignant transformation. Cold Spring Harbor Conf. Cell Proliferation, 6: 219–238, 1979.
36. Quigley, J. P. Ossowski, L. and Reich, E. Plasminogen: the serum proenzyme activated by factors from cells transformed by oncogenic viruses. J. Biol. Chem. 249: 4306–4311, 1974.
37. Reich, E. Activation of plasminogen: A widespread mechanism for generating localized extracellular proteolysis. In: R. W. Ruddon (ed.), Biological Markers of Neoplasia: Basic and Applied Aspects, pp. 491–500. Amsterdam: Elsev-ier/North-Holland Biomedical Press. 1978.
38. Rhodes, K. R. and Miller, E. J. Physicochemical characterization and molecular organization of the collagen A and B chains. Biochemistry, 17: 3442–3448. 1978.
39. Robbins. K. C. Summaria, L. and Barlow, G. H. Activation of plasminogen. Cold Spring Harbor Conf. Cell Proliferation, 2: 305–310, 1975.
40. Shulman, N. R., and Tagnon, H. J. Proteolytic activity determined with a substrate tagged with radioactive iodine. J. Biol. Chem. 186:69-75, 1950.
41. Terranova, V. P., Rohrback, D. H., and Martin, G. R. Role of laminin in the attachment of PAM 212 (epithelial) cells to basement membrane collagen. Cell. 22: 719–726. 1980.
42. Timpl, R. Martin, G. R. Bruckner, P., Wick, G. and Wiedemann, H. Nature of the collagenous protein in tumor basement membrane. Eur. J. Biochem., 84: 43–49, 1978.
43. Timpl, R., Rohde. H., Gehron-Robey, P., Rennard, S., Foidart, J. M., and Martin, G. R. Laminin—a glycoprotein of basement membranes. J. Biol. Chem., 254: 9933–9937, 1979.
44. Tryggvason, K. Gehron-Robey, P., and Martin, G. R. Biosynthesis of type IV procollagens. Biochemistry, 19: 1284–1289, 1980.
45. Unkeless. J. C., Dano, K., Kellerman, G. M., and Reich, E. Fibrinolysis associated with oncogenic transformation. Partial purification and characterization of the cell factor, a plasminogen activator. J. Biol. Chem., 249: 4295–4305, 1974.
46. Vetterlein, D. Young, P. Y., Bell. T. E. and Roblin, R. Immunological characterization of multiple molecular weight forms of human cell plasminogen activators. J. Biol. Chem., 254: 575–578, 1979.
47. Vlaeminck, M. N., Adenis, L., Mouton, Y., and Demaille, A. Etude experimentale de la diffusion metastatique chez I'oeuf de poule embryonne. Repartition, microscopic et ultrastructure des foyers tumoraux. Int. J. Cancer. 70: 619–631, 1972.
48. Vracko, R. Basal lamina scaffold—anatomy and significance for maintenance of orderly tissue structure. Am. J. Pathol. 77: 314–338, 1974.
49. Wallace. A. C., Chew, E., and Jones, D. S. The arrest and extravasation of cancer cells in the lung. In: L. Weiss and H. A. Gilbert (eds.). Pulmonary Metastasis, Vol. 3, pp. 26–42. Boston: G. K. Hall. 1978.
50. White, W. F., Barlow, G.H., and Mozen, M. M. The isolation and characterization of plasminogen activators (Urokinase) from human urine. Biochemistry. 5: 2160–2169, 1966.
51. Wilson, E. L., Becker, M. L. Hoal, E. G., and Dowdle, E. B. Molecular species of plasminogen activators secreted by normal and neoplastic human cells. Cancer Res. 40: 933–938, 1980.