Adaptation Versus Selection as the Mechanism Responsible for the Relapse of Prostatic Cancer to Androgen Ablation Therapy as Studied in the Dunning R-3327-H Adenocarcinoma

Cancer Research

Volumn 41, Issue , 1981, Pages 5070-5074

  Isaacs, John T ^a   Coffey, Donald S ^b  

^a JOHNS HOPKINS HOSPITAL   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; HORMONE RECEPTOR; TESTOSTERONE PROPIONATE;

ADAPTATION; ANIMAL EXPERIMENT; CANCER RECURRENCE; IN VITRO STUDY; MALE GENITAL SYSTEM; PROSTATE CANCER; RAT; RECURRENT DISEASE;

ADAPTATION, PHYSIOLOGICAL; ADENOCARCINOMA; ANIMAL; CASTRATION; MALE; NEOPLASMS, EXPERIMENTAL; PROSTATIC NEOPLASMS; RATS; SELECTION (GENETICS); SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0019841416     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. Coffey, D. S., Shimazaki, J., and Williams-Ashman, H. G. Polymerization of deoxyribonucleotides in relation to androgen-induced prostatic growth. Arch. Biochem. Biophys., 124: 184–198, 1968.
2. Isaacs, J. T., and Coffey, D. S. Animal models in the study of prostatic cancer. Cancer Detection Prevention, 2: 587–599, 1979.
3. Janek, P., Briand, P., and Hartmann, N. R. The effects of estrone-progesterone treatment on cell proliferation kinetics of hormone-dependent GR mouse mammary tumors. Cancer Res., 35: 3698–3704, 1975.
4. Menon, M., and Walsh, P. C. Hormonal therapy for prostatic cancer. In: G. P. Murphy (ed.), Prostatic Cancer, pp. 175–200. Littleton, Mass.: PSP Publishing Co., 1979.