New synthetic inhibitors of C1r̄, C1 esterase, thrombin, plasmin, kallikrein and trypsin

BBA - Enzymology

Volumn 661, Issue 2, 1981, Pages 342-345

  Fujii, Setsuro ^a   Hitomi, Yuji ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

C1 esterase; C1r ; Kallikrein; Plasmin; Protease inhibitor; Thrombin; Trypsin

Indexed keywords

COMPLEMENT COMPONENT C1S INHIBITOR; ESTERASE; FUT 5895; FUT 5897; KALLIKREIN; NAFAMSTAT MESILATE; PLASMIN; PROTEINASE INHIBITOR; THROMBIN; TRYPSIN; UNCLASSIFIED DRUG;

4 (3 AMIDINOVINYL)PHENYL 4 GUANIDINOBENZOIC ACID DIMETHANESULFONIC ACID; 4 AMIDINO 2 BENZOYLPHENYL 4 GUANIDINOBENZOIC ACID DIMETHANESULFONIC ACID; 6 AMIDINO 4 GUANIDINO 2 NAPHTHYLBENZOIC ACID; BLOOD AND HEMOPOIETIC SYSTEM; COMPLEMENT SYSTEM; DRUG COMPARISON; GUANIDINOBENZOIC ACID DERIVATIVE; HEMOLYSIS; IN VITRO STUDY; MAMMAL; STRUCTURE ACTIVITY RELATION;

COMPLEMENT 1 INACTIVATORS; COMPLEMENT 1R; COMPLEMENT ACTIVATING ENZYMES; ENZYME PRECURSORS; GUANIDINES; HUMAN; KALLIKREINS; PLASMIN; PROTEASE INHIBITORS; THROMBIN; TRYPSIN INHIBITORS;

EID: 0019817468     PISSN: 00052744     EISSN: None     Source Type: Journal    
DOI: 10.1016/0005-2744(81)90023-1     Document Type: Article

References (17)

1. Inhibitory effects of ω-amino acid esters on trypsin, plasmin, plasma kallikrein and thrombin
2. Inhibitory effects of ω-guanidino acid esters on trypsin, plasmin, plasma kallikrein and thrombin
3. Inhibitory effects of ω-amino and ω-guanidino acid esters on the first component of human complement
4. Irreversible enzyme inhibitors. CLXIV. Proteolytic enzymes. 14. Inhibition of guinea pig complement by meta-substituted benzamidines