Effect of berberine on bile secretion in rats—with special reference to erythritol and sucrose clearances and liver microsomal functions

Acta Hepatologica Japonica

Volumn 22, Issue 8, 1981, Pages 1128-1134

  Obata, Takahiro ^a   Hobara, Norio ^a   Higashi, Toshihiro ^a   Hayashi, Shosaku ^a   Takei, Nobuyuki ^a   Watanabe, Akiharu ^a   Nagashima, Hideo ^b  

^a Okayama University Medical School ^*  (Japan)

^b OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BERBERINE; BILE ACID; BILIRUBIN; CYTOCHROME P450; GLUCURONOSYLTRANSFERASE; RADIOISOTOPE;

ALPHA HYDROXYCYCLOHEXYLBUTYRIC ACID; ANIMAL EXPERIMENT; BILE SECRETION; BILIARY EXCRETION; ERYTHRITOL C 14; INTRAVENOUS DRUG ADMINISTRATION; LIVER; LIVER FUNCTION; LIVER MICROSOME; RAT; SUCROSE C 14;

EID: 0019802425     PISSN: 04514203     EISSN: 18813593     Source Type: Journal    
DOI: 10.2957/kanzo.22.1128     Document Type: Article

References (10)

1. Oshiba S et al: Effect of berberine in bile secretion. Nihon Univ J Med 16: 69, 1974
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3. Omura T, Sato R: The carbon monoxide-binding pigment of liver microsomes. II. Solubilization, purification, and properties. J Biol Chem 239: 2379, 1964
4. Frei J: Multiplicity and specificity of UDP-glucuronyl-transferase. I. Effect of divalent cations and EDTA on the activity of UDP-glucuronyltransferase assayed with Bilirubin, 4-methylumbelliferone and p-nitrophenol. Enzym Biol Clin 11: 385, 1970
5. Lowry OH et al: Protein measurement with the folin phenol reagent. J Biol Chem 193: 265, 1951
6. Hobara N et al: Effect of berberine on bile secretion in rat. Pharmacology, in press
7. (guinea pig) 20: 49, 1979
8. Motoyama Y: Studies of human liver bilirubin-glycosyl transferase Bilirubin UDP-xylosyl and UDP-glucuronyl transferase activities in diseased human livers. Enzyme 24: 158, 1979
9. Kuwano S et al: Effects of berberine on tyrosine decarboxylase activity of Streptococcus faecalis. Chem Pham Bull 8: 491, 1960
10. Kuwano S et al: Effects of berberine with pyridoxal phosphate in the tryptophanase system of Escherichia Coli. Chem Pham Bull 8: 497, 1960