Understanding the Dose-Effect Relationship: Clinical Application of Pharmacokinetic-Pharmacodynamic Models

Clinical Pharmacokinetics

Volumn 6, Issue 6, 1981, Pages 429-453

  Holford, Nicholas H G ^a,b,c   Sheiner, Lewis B ^a,b  

^a School of Medicine and Pharmacy   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACECAINIDE; CHLOROTHIAZIDE; CIMETIDINE; COCAINE; CYCLOPHOSPHAMIDE; DIGITOXIN; DIGOXIN; EPHEDRINE; GENTAMICIN; ISOPRENALINE; LYSERGIDE; OUABAIN; PHENOBARBITAL; PHENYLBUTAZONE; PHENYTOIN; PREDNISONE; PROCAINAMIDE; PROPRANOLOL; QUINIDINE; THEOPHYLLINE; TOBRAMYCIN; TOCAINIDE; TUBOCURARINE CHLORIDE; VERAPAMIL; WARFARIN;

BIOAVAILABILITY; DOSE RESPONSE; DRUG RESPONSE; MATHEMATICAL MODEL; METHODOLOGY; MODEL; NONBIOLOGICAL MODEL; PHARMACODYNAMICS; PHARMACOKINETICS; SHORT SURVEY;

BIOLOGICAL AVAILABILITY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; DRUG HYPERSENSITIVITY; DRUG TOLERANCE; HUMAN; KINETICS; MODELS, BIOLOGICAL; PHARMACEUTICAL PREPARATIONS; PROTEIN BINDING; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0019785890     PISSN: 03125963     EISSN: 11791926     Source Type: Journal    
DOI: 10.2165/00003088-198106060-00002     Document Type: Article

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