Transport of steroid hormones: Binding of 21 endogenous steroids to both testosterone-binding globulin and corticosteroid-binding globulin in human plasma

Journal of Clinical Endocrinology and Metabolism

Volumn 53, Issue 1, 1981, Pages 58-68

  Dunn, James F ^a   Nisula, Bruce C ^a   Rodbard, David ^a,b  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b Biophysical Endocrinology Section ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TESTOSTERONE; TRANSCORTIN;

BLOOD AND HEMOPOIETIC SYSTEM; DIAGNOSIS; ENDOCRINE SYSTEM; HUMAN; HUMAN EXPERIMENT; NORMAL HUMAN; PRELIMINARY COMMUNICATION;

ADRENAL CORTEX HORMONES; ANDROGENS; BIOLOGICAL TRANSPORT; COMPUTERS; ESTROGENS; FEMALE; HUMAN; HYDROCORTISONE; MALE; MODELS, BIOLOGICAL; PREGNANCY; PROGESTERONE; SERUM ALBUMIN; SEX FACTORS; SEX HORMONE-BINDING GLOBULIN; TESTOSTERONE; TRANSCORTIN;

EID: 0019759637     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jcem-53-1-58     Document Type: Article

References (50)

1. Heyns W, Van Baelen H, DeMoor P 1967 Study of steroid-protein binding by means of competitive adsorption: application to cortisol binding in plasma. Clin Chem Acta 18:361
2. Nisula BC, Dunn JF 1979 Measurement of the testosterone binding parameters for both testosterone-estradiol binding globulin and albumin in individual seum samples. Steroids 34:771
3. Lea OA 1979 Interaction of steroid-binding serum proteins with concanavalin A-Sepharose 4B. Horm Res 11:240
4. Rodbard D, Lewald JE 1970 Computer analysis of radioligand assay and radioimmunoassay data (Appendix III). Acta Endocrinol [Supp 147]64:79
5. Feldman H, Rodbard D, Levine D 1972 Mathematical theory of cross-reactive radioimmunoassay and ligand-binding systems at equilibrium. Anal Biochem 45:530
6. Westphal U 1971 Steroid-Protein Interactions, Springer-Verlag, New York
7. Clark AF, Baird CE 1973 Binding of 5α-androstane-3α, 17β-diol to human plasma proteins. J Endocrinol 57:289
8. Burke CW, Anderson DC 1972 Sex-hormone-binding globulin is an oestrogen amplifier. Nature 240:38
9. Hammond GL, Ruokonen A, Kontturi M, Koskela E, Vihko R 1977 The simultaneous radioimmunoassay of seven steroids in human spermatic and peripheral venous blood. J Clin Endocrinol Metab 45:16
10. Weitzman ED, Fukushima D, Nogeire C, Roffwarg H, Gallagher TF, Heilman L 1971 Twenty-four hour pattern of the episodic secretion of cortisol in normal subjects. J Clin Endocrinol Metab 33:14
11. Spark RF, Kettyle WR, Eisenberg H 1974 Cortisol dynamics in the adrenal venous effluent. J Clin Endocrinol Metab 39:503
12. Westphal U 1966 Steroid-protein interactions. XII. Distribution of progesterone and corticosteroid hormones among serum proteins. Z Physiol Chem 346:243
13. Brown-Grant K, Brennan RD, Yates FE 1970 Simulation of the thyroid hormone-binding protein interactions in human plasma. J Clin Endocrinol Metab 30:733
14. Vermeulen A 1977 Transport and distribution of androgens at different ages, In: Martini L, Motta M (eds) Androgens and Antiandrogens, Raven Press, New York, p 53
15. Lutz RA, Lutz-Ewan L, Weder HG 1973 Further studies on the temperature dependence of the binding of testosterone to human pregnancy plasma proteins. Steorids 21:423
16. Stroupe SD, Harding GB, Forsthoefel MW, Westphal U 1978 Kinetic and equilibrium studies on steroid interaction with human corticosteroid-binding globulin. Biochemistry 17:177
17. Sandberg AA, Rosenthal H, Schneider SL, Slaunwhite Jr WR 1966 Protein-steroid interactions and their role in the transport and metabolism of steroids, In: Pincus G, Nakao T, Tait JF (eds) Steroid Dynamics, Academic Press, New York, p 1
18. Vermeulen A, Verdonk L 1968 Studies on the binding of testoster-one to human plasma. Steroids 11:609
19. Kato T, Horton R 1968 Studies of testosterone binding globulin. J Clin Endocrinol Metab 28:1160
20. Rosner W 1976 The binding of steroid hormones in human serum. In: Jamieson G A, Greenwalt TJ (eds) Trace Components of Plasma: Isolation and Clinical Significance, Alan R. Liss, Inc., New York, p 377
21. Heyns W 1977 The steroid-binding β-globulin of human plasma, In: Briggs MH, Christie GA (eds) Advances in Steroid Biochemistry and Pharmacology. Academic Press, New York, vol 6:59
22. Ojasoo T, Raynaud J-P 1978 Unique steroid congeners for receptor studies. Cancer Res 38:4186
23. Bernutz C, Hansle WO, Horn K, Pickardt CR, Scriba PC, Fink E, Kolb H, Tschesche H 1979 Isolation, characterization and radioim-munoassay of corticosteroid-binding globulin (CBG) in human se-rum—clinical significance and comparison to thyroxine-binding globulin (TBG). Acta Endocrinol 92:370
24. Lata GF, Hu H-K, Bagshaw G, Tucker RF 1980 Equilibrium and kinetic characteristics of steroid interactions with human plasma sex steroid binding protein. Arch Biochem Biophys 199:220
25. Fisher RA, Burke CW 1974 Simultaneous measurement of unbound testosterone and estradiol fractions in undiluted plasma at 37° C by steady-state gel filtration. Steroids 24:809
26. Hammond GL, Nisker JA, Jones LA, Siiteri PK 1980 Estimation of the percentage of free steroid in undiluted serum by centrifugal ultrafiltration-dialysis. J Biol Chem 255:5023
27. Moll Jr GW, Rosenfield RL 1979 Testosterone binding and free plasma androgen concentrations under physiologic conditions: characterization by flow dialysis technique. J Clin Endocrinol Metab 49:730
28. Zipser RD, Meidar V, Horton R 1980 Characteristics of aldosterone binding in human plasma. J Clin Endocrinol Metab 50:158
29. Rosner W, Smith RN 1975 Isolation and characterization of the testosterone-estradiol-binding globulin from human plasma. Use of a novel affinity column. Biochemistry 14:4813
30. Wu CH, Motohashi T, Abdel-Rahman HA, Flickinger GL, Mikhail G 1976 Free and protein-bound plasma estradiol-17β during the menstrual cycle. J Clin Endocrinol Metab 43:436
31. Dunn JF, Merriam GR, Eil C, Kono S, Loriaux DL, Nisula BC 1980 Testosterone-estradiol binding globulin binds to 2-methoxyestra-diol with greater affinity than to testosterone. J Clin Endocrinol Metab 51:404
32. Durber SM, Daly JR 1976 A simple method for the determination of free cortisol in plasma, with normal levels in men and women, including women taking low estrogen contraceptives. Clin Chim Acta 68:43
33. Robin P, Predine J, Milgrom E 1977 Assay of unbound cortisol in plasma. J Clin Endocrinol Metab 46:277
34. Schoneshofer M, Wagner GG 1977 Sex differences in corticosteroids in man. J Clin Endocrinol Metab 45:814
35. Gandy HM 1977 Androgens, In: Fuchs F, Klopper A (eds) Endocrinology of Pregnancy, Harper & Row, Hagerstown, MD, p 123
36. Rosenfield RL, Otto P 1972 Androstenediol levels in human peripheral plasma. J Clin Endocrinol Metab 35:818
37. Kream J, Heilman L, Rosenfeld RS 1976 Radioimmunoassay of androsterone and androsterone-3-sulfate in plasma. Steroids 27:727
38. Srivastava LS, Werk Jr EE, Thrasher K, Sholiton LJ, Kozera R, Nolten W, Knowles Jr HC 1973 Plasma cortisone concentration as measured by radioimmunoassay. J Clin Endocrinol Metab 36:937
39. Wright K, Collins DC, Preedy JRK 1978 The use of specific radioimmunoassays to determine the renal clearance rates of estrone and 17β-estradiol during the menstrual cycle. J Clin Endocrinol Metab 47:1084
40. Chung-Hsiu W, Lundy LE 1971 Radioimmunoassay of plasma estrogens. Steroids 18:91
41. Sato K, Ohsawa N 1977 Radioimmunoassay for etiocholanolone. Steroids 29:295
42. Abraham GE, Buster JE, Kyle FW, Corrales PC, Teller RC 1973 Radioimmunoassay of plasma pregnenolone. J Clin Endocrinol Metab 37:40
43. McKenna TJ, DiPietro DL, Brown RD, Strott CA, Liddle GW 1974 Plasma 17-OH-pregnenolone in normal subjects. J Clin Endocrinol Metab 39:833
44. Nisula BC, Loriaux DL, Wilson YA 1978 Solid phase method for the measurement of the binding capacity of testosterone-estradiol binding globulin in human serum. Steroids 31:681
45. Nolten WE, Lindheimer MD, Oparil S, Ehrlich EN 1978 Desoxy-corticosterone in normal pregnancy. Am J Obstet Gynecol 132:414
46. Weir RJ, Paintin DB, Brown JJ Fraser R, Lever AF, Robertson JIS, Young J 1971 A serial study in pregnancy of the plasma concentrations of renin, corticosteroids, electrolytes and proteins and of haematocrit and plasma volume. J Obstet Gynecol Br Commonw 78:590
47. Rosenthal HE, Slaunwhite Jr WR, Sandberg AA 1969 Transcortin: a corticosteroid-binding protein of plasma. X. Cortisol and proges-terone interplay and unbound levels of these steroids in pregnancy. J Clin Endocrinol Metab 29:352
48. Cawson MJ, Anderson ABM, Turnbull AC, Lampe L 1974 Cortisol, cortisone, and 11-deoxycortisol levels in human umbilical and maternal plasma in relation to the onset of labour. J Obstet Gynecol Br Commonw 81:737
49. Tulchinsky D, Hobel CJ, Yeager E, Marshall JR 1972 Plasma estrone, estradiol, estriol, progesterone and 17-hydroxyprogester-one in human pregnancy. Am J Obstet Gynecol 112:1095
50. Abraham GE, Buster JE, Kyle FW, Corrales PC, Teller RC 1973 Radioimmunoassay of plasma pregnenolone, 17-hydroxypregneno-lone and dehydroepiandrosterone under various physiological conditions. J Clin Endocrinol Metab 37:140