A review of theoretical aspects of HLA and disease associations

Theoretical Population Biology

Volumn 20, Issue 2, 1981, Pages 168-208

  Thomson, Glenys ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIGEN;

ALLELE; ARTICLE; CHROMOSOME MAP; GENE; GENE FREQUENCY; GENETIC VARIABILITY; GENETICS; GENOTYPE; HAPLOIDY; HUMAN;

ALLELES; CHROMOSOME MAPPING; GENE FREQUENCY; GENES; GENOTYPE; HAPLOIDY; HLA ANTIGENS; HUMAN; SUPPORT, U.S. GOV'T, P.H.S.; VARIATION (GENETICS);

EID: 0019631518     PISSN: 00405809     EISSN: 10960325     Source Type: Journal    
DOI: 10.1016/0040-5809(81)90009-5     Document Type: Review

References (115)

1. Genetics of the HL-A system in four populations: American Caucasians, Japanese Americans, American Negroes and Mexican Americans
2. Study of the leucocyte phenotypes in Hodgkin's disease
3. Analysis of linkage between the major histocompatibility system and juvenile, insulin-dependent diabetes in multiplex families
4. Genetic structure of major histocompatibility regions
5. Measuring the strength of associations between HLA antigens and diseases
6. The search for a human equivalent of the mouse T-locus-negative results from a study of HL-A types in spina bifida
7. Studies on African pygmies. IV. A comparative study of the HL-A polymorphism in the Babinga pygmies and other African and Caucasian populations
8. Evolutionary significance of the HL-A system
9. Evolution of HL-A and other major histocompatibility systems
10. The HLA system
11. HLA: A super supergene
12. The HLA system: Introduction
13. The HLA system and disease
14. The HLA histocompatibility antigens and disease
15. Evolution and function of the HLA system
16. Genetics of HLA The major human histocompatibility system
17. The genetic analysis of HLA and disease associations
18. Histocompatibility antigens as markers of abnormal iron metabolism in patients with idiopathic haemochromatosis and their relatives
19. Genetics of leukocyte antigens. A family study of segregation and linkage
20. Evidence for HLA linked genes in “juvenile” diabetes mellitus
21. A note on relative risks
22. Disease susceptibility genes—their identification by multiple case family studies
23. Bf and C4 markers for insulin-dependent diabetes in Basques
24. HLA-phenotype and hemocrhomatosis in Germany
25. Sequential studies in ankylosing spontylitis: Association of Klebsiellia pneumoniae with active disease
26. The inheritance of liability to diseases with variable age of onset, with particular reference to diabetes mellitus
27. The effect of association of genetic factors on relative risk
28. The major histocompatibility complexes
29. Sibling method for detecting HLA-linked genes in disease
30. Investigations of a two locus model for coeliac disease
31. The estimation and significance of the logarithm of a ratio of frequencies
32. HLA in patients with coeliac disease and their families
33. Multilocus system in evolution
34. Some epistatic two locus models of disease I Relative risks and identity-by-descent distributions in affected sib pairs
35. A three allele model for heterogeneity of juvenile onset diabetes mellitus
36. Does an HLA-disease association necessarily imply tight linkage?
37. Some epistatic two-locus models of disease II The confounding of linkage and associations
38. Studies on artificial antigens. I. Antigenicity of DNP-polylysine and DNP copolymer of lysine and glutamic acid in guinea pigs
39. Statistical methods for assessing linkage disequilibrium at the HLA-A B C loci
40. HLA-Dw3 associated with coeliac disease
41. Studies of the gnetics of illnesses associated with HLA
42. Genetic Analysis of HLA-associated diseases: The “illness susceptible” gene frequency and sex ratio in ankylosing spondylitis
43. A Beyesian method for estimation of HLA-associated illness-susceptibility (Is) allele frequencies. I. Dominant susceptibility
44. Survival process of linked mutant genes
45. Genetic linkage between hereditary hemochromatosis and HLA
46. Studies on artificial antigens. III. The genetic control of the immune response to haptenpoly-L-lysine conjugates in guinea pigs
47. Genetic basis of susceptibility to viral leukaemogenesis
48. Hemochromatose idiopathique liaison avec le systmème HLA
49. Statistical aspects of the analysis of data from retrospective studies of disease
50. New approaches to the population genetic and segregation analysis of the HL-A system
51. The hitch-hiking effect of a favourable gene
52. Genetic structure and functions of the major histocompatibility complex
53. Histocompatibility antigens, immune responsiveness and susceptibility to disease
54. HLA-A, immune-response genes, and disease
55. Genetic control of the antibody response. I. Demonstration of determinant-specific differences in response to synthetic polypeptide antigens in two strains of inbred mice
56. Genetic control of the antibody response. II. Further analysis of the specificity of determinant-specific control, and genetic analysis of the response to (H, G)-A-L in CBA and C7 mice
57. The association between the HLA system and disease
58. The effect of selected linked locus on heterozygosity of neutral alleles (the hitch-hiking effect)
59. Genetic basis of glutensensitive enteropathy
60. The detection of autosomal linkage in data which consists of pairs of brothers and sisters of unspecified parentage
61. Detection of HLA haplotype associations with diseases
62. Diabetes mellitus in identical twins
63. HLA and disease susceptibility: A primer
64. Heterogeneity in diabetes mellitus—Update, 1978
65. HLA studies in diabetes
66. Evidence for a specific B27-associated cell surface marker on lymphocytes of patients with ankylosing spondylitis
67. HLA antigens in haemochromatosis
68. Hémochromatose idiopathique. Maladie associée à l'antigene tissulaire HL-A3?
69. Association of HLA-A3 and HLA-B14 antigens with idiopathic hemochromatosis
70. Heredity of idiopathic haemochromatosis: A study of 106 families
71. Idiopathic Hemochromatosis: demonstration of recessive transmission and early detection by family HLA typing
72. Increased risk in Chinese for nasopharyngeal carcinoma associated with a Chinese related HL-A profile
73. Statistical analysis of HLA-disease associations
74. Juvenile-onset diabetes: HLA-A, -B, -C and -DR alloantigens
75. Genetics of juvenile diabetes: Dosage of susceptibility genes
76. Inheritance of susceptibility to juvenile onset diabetes
77. Gene dosage and susceptibility to insulin dependent diabetes
78. HLA family studies and multiple sclerosis A common gene dominantly expressed
79. The affected sib pair IBD distribution for HLA-linked disease susceptibility genes
80. Estimating the parameters of the incompletely penetrant single locus using multiple populations
81. Is juvenile diabetes determined by a single gene closely linked to HLA?
82. HL-A antigens and disease statistical and gnetical considerations
83. HL-A and disease associations—a survey
84. Associations between HLA and disease
85. Simple estimation of population attributable risk from casecontrol studies
86. HL-A haplotype of 32 diseases
87. The effect of a selected locus on linked neutral loci
88. A two locus model for juvenile diabetes
89. The genetics of HLA abd disease associations
90. The genetic analysis of HLA and disease associations
91. The HL-A system as a model for studying the interaction between selection, migration, and linkage
92. HLA and the inheritance of multiple sclerosis: linkage analysis of 72 pedigrees
93. Ankylosing spondylitis (AS): A population and family study using HL-A serology and MIR
94. Ethnic variation in genetic disease: possible roles of hitchhiking and epistasis
95. HLA antigens in haemochromatosis
96. Preferential zygotic assortment of certain HLA haplotypes
97. On estimating the relation between blood group and disease