Substituted benzimidazoles inhibit gastric acid secretion by blocking (H+ + K+) ATPase

Nature

Volumn 290, Issue 5802, 1981, Pages 159-161

  Fellenius, Erik ^a   Berglindh, Thomas ^b   Sachs, George ^c   Olbe, Lars ^d   Elander, Berit ^a   Sjöstrand, Sven Erik ^a   Wallmark, Björn ^a  

^a ASTRAZENECA R AND D   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; AMINOPHENAZONE C 14; ATROPINE; BENZIMIDAZOLE; BUCLADESINE; CIMETIDINE; H 14994; HISTAMINE; RADIOISOTOPE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; IN VITRO STUDY; RABBIT; STOMACH; STOMACH ACID SECRETION; STOMACH GLAND; STOMACH MUCOSA; STRUCTURE ACTIVITY RELATION;

2-PYRIDINYLMETHYLSULFINYLBENZIMIDAZOLES; ADENOSINE TRIPHOSPHATASES; AMINOPYRINE; ANIMALS; ATROPINE; BENZIMIDAZOLES; BUCLADESINE; CIMETIDINE; GASTRIC ACID; GASTRIC MUCOSA; H(+)-K(+)-EXCHANGING ATPASE; HISTAMINE; OMEPRAZOLE; POTASSIUM; RABBITS;

ANIMALIA; ORYCTOLAGUS CUNICULUS; SUS SCROFA;

EID: 0019496870     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/290159a0     Document Type: Article

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