Effect of surfactants on the nasal absorption of insulin in rats

International Journal of Pharmaceutics

Volumn 9, Issue 2, 1981, Pages 165-172

  Shinichiro, Hirai ^a   Takatsuka, Yashiki ^a   Hiroyuki, Mima ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; SURFACTANT;

ANIMAL EXPERIMENT; DRUG ABSORPTION; NOSE; RAT; RESPIRATORY SYSTEM;

EID: 0019488704     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(81)90009-0     Document Type: Article

References (19)

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4. 12 from ligated stomach and intact intestine of the rat
5. Normal and promoted gastrointestinal absorption of water-soluble substances I: Induced rapidly reversible hyperabsorptive state in the canine stomach pouch
6. Effect of surfactant on absorption through membranes V: Concentration-dependent effect of a bile salt (sodium deoxycholate) on absorption of a poorly absorbable drug, phenolsulfonphthalein, in humans
7. Nasal absorption of insulin in dogs
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9. Specific determination of blood glucose with o-toluidine
10. Rectal absorption of insulin suppositories in rabbits
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12. Effect of surfactants on absorption through membranes IV: Effects of dioctyl sodium sulfosuccinate on absorption of a poorly absorbable drug, phenolsulfonphthalein, in humans
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14. Effect of complex formation on drug absorption III. Concentration and drug dependent effect of a nonionic surfactant
15. Effect of surface active agent on insulin absorption upon rectal administration of insulin suppository to rabbits
16. Short-term treatment of alloxane-diabetic rats with intrajejunal administration of water-in-oil-in-water insulin emulsions
17. Surfactant effects on drug absorption III: Effects of sodium glycocholate and its mixtures with synthetic surfactants on absorption of thiamine disulfide compounds in rat
18. Insulin across respiratory mucosae by aerosol delivery
19. Nasal and sublingual administration of insulin in man