The induction of chromosome-type aberrations in G1 by methyl methanesulfonate and 4-nitroquinoline-N-oxide, and the non-requirement of an S-phase for their production

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 83, Issue 3, 1981, Pages 395-402

  Preston, R J ^a   Gooch, P C ^a  

^a OAK RIDGE NATIONAL LABORATORY   (United States)

Author keywords

4 nitroquinoline N oxide; 4NQO; ara C; cytosine arabinoside; Hanks' balanced salt solution; HBSS; methyl methanesulfonate; MMS

Indexed keywords

4 NITROQUINOLINE 1 OXIDE; CYTARABINE; MESYLIC ACID METHYL ESTER;

BLOOD AND HEMOPOIETIC SYSTEM; CELL CULTURE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CHROMOSOME ABERRATION; DNA REPAIR; HEREDITY; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHATIC SYSTEM; LYMPHOCYTE; NORMAL HUMAN;

4-NITROQUINOLINE-1-OXIDE; CELLS, CULTURED; CHROMOSOME ABERRATIONS; CHROMOSOMES; CYTARABINE; DRUG THERAPY, COMBINATION; HUMAN; INTERPHASE; LYMPHOCYTES; METHYL METHANESULFONATE; MUTAGENS; SUPPORT, U.S. GOV'T, NON-P.H.S.;

EID: 0019478968     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/0027-5107(81)90021-X     Document Type: Article

References (14)

1. Radiation-induced human chromosome aberrations, II. Human in vitro irradiation compared to in vitro and in vivo irradiation of marmoset leukocytes
2. Inhibition of DNA excision repair in human cells by arabinofuranosyl cytosine: Effect on normal and xeroderma pigmentosum cells
3. Molecular mechanisms in the induction of chromosome aberrations
4. The relation between DNA synthesis and chromosome structure as resolved by X-ray damage
5. Influence of DNA synthesis on the production of chromatid aberrations by X-rays and maleic hydrazide in Vicia faba
6. The induction of chromosome aberrations by nitrogen mustard and its dependence on DNA synthesis
7. The effect of cytosine arabinoside on the frequency of single strand breaks in DNA of mammalian cells following irradiation or chemical treatment
8. The repair of methyl methanesulfonate-induced lesions in the DNA of a murine lymphoma cell
9. 2 state of cell cycle
10. The effect of cytosine arabinoside on the frequency of X-ray-induced chromosome aberrations in normal human leukocytes
11. DNA repair capacity and susceptibility to chromosome breakage in xeroderma pigmentosum cells
12. The repair of bleomycin-induced DNA damage and its relationship to chromosome aberration repair
13. Chromosome splitting as revealed by combined X-ray and labeling experiments