Reduction in immunogenicity and clearance rate of Escherichia coli L-asparaginase by modification with monomethoxypolyethylene glycol

Journal of Pharmacology and Experimental Therapeutics

Volumn 216, Issue 2, 1981, Pages 410-414

  Kamisaki, Y ^a   Wado, H ^a   Yagura, T ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINASE; ENZYME;

ANIMAL EXPERIMENT; DRUG BLOOD LEVEL; DRUG CLEARANCE; ESCHERICHIA COLI; HEREDITY; IMMUNOGENICITY; INTRAPERITONEAL DRUG ADMINISTRATION; METHOXYPOLYETHYLENE GLYCOL; MOUSE; PHARMACOKINETICS; RAT;

ANIMAL; ANTIBODY FORMATION; ASPARAGINASE; ASPARAGINE; ESCHERICHIA COLI; ETHYLENE GLYCOLS; FEMALE; KINETICS; MALE; METABOLIC CLEARANCE RATE; MICE; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T;

EID: 0019461927     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (0)