A New and Efficient Total Synthesis of Streptonigrin

Journal of the American Chemical Society

Volumn 103, Issue 5, 1981, Pages 1271-1273

  Kende, Andrew S ^a   Lorah, Dennis P ^a   Boatman, Rodney J ^a  

^a UNIVERSITY OF ROCHESTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RUFOCROMOMYCIN;

DRUG ANALYSIS; DRUG IDENTIFICATION; DRUG SYNTHESIS; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE; PRELIMINARY COMMUNICATION; THEORETICAL STUDY; THIN LAYER CHROMATOGRAPHY; ULTRAVIOLET SPECTROPHOTOMETRY;

EID: 0019445632     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja00395a071     Document Type: Article

References (15)

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2. For a review, see: Hibino, S. Heterocycles 1977, 6, 1485.
3. Kende, A. S.; Naegely, P. C. Tetrahedron Lett. 1978, 4775. (b)Kim, D.; Weinreb, S. M. J. Org. Chem. 1978, 43, 121.
4. Tetrahedron Lett. 1978, 43,125.
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6. For fascinating recent studies on the biosynthesis of streptonigrin, see:Gould, S. J.; Darling, D. S. Tetrahedron Lett. 1978, 3207. Gould, S. J.;Chang, C. C. J. Am. Chem. Soc. 1977, 99, 5496; 1978, 100, 1624; 1980,102,1702. Gould, S. J. Chang, C. C.; Darling, D. S.; Roberts, J. D.; Squillacote,M. Tetrahedron Lett…. 1980, 102, 1707.
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12. Dry, degassed solvent and potassium metal purified by the procedureof Pearson were employed, cf.: Pearson, D. E.; Keaton, O. D. J. Org. Chem. 1963, 28, 1557.
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