Effect of strict blood glucose control on residual B-cell function in insulin-dependent diabetics

Diabetologia

Volumn 20, Issue 5, 1981, Pages 530-534

  Madsbad, S ^a   Krarup, T ^a   Regeur, L ^a   Faber, O K ^a   Binder, C ^a  

^a STENO DIABETES CENTER   (Denmark)

Author keywords

B cell function; C peptide; endogenous insulin secretion; Glycaemic control; insulin dependent diabetics

Indexed keywords

DIABETES MELLITUS; ENDOCRINE SYSTEM; ETIOLOGY; MAJOR CLINICAL STUDY; PANCREAS ISLET BETA CELL; THERAPY;

ADOLESCENT; ADULT; BLOOD GLUCOSE; C-PEPTIDE; DIABETES MELLITUS; FEMALE; HUMANS; INSULIN; ISLETS OF LANGERHANS; MALE;

EID: 0019436047     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/BF00252760     Document Type: Article

References (23)

1. Beta-cell function in children with diabetes
2. Beta-cell function during initial treatment in insulin dependent diabetics
3. Sequential changes in beta-cell function in insulin-treated diabetic patients assessed by C-peptide immunoreactivity
4. Serum-insulin in remission of juvenile diabetes
5. Weber B (1972) Glucose stimulated insulin secretion during remission of juvenile diabetes. Diabetologia 189–195
6. C-peptide in juvenile diabetics beyond the post-initial remission period
7. Control of juvenile diabetes mellitus and its relationship to endogenous insulin secretion as measured by C-peptide immunoreactivity
8. Metabolic control in diabetic patients. Effect of insulin-secretory reserve (measured by plasma C-peptide levels) and circulating insulin antibodies
9. Role of residual insulin secretion in protecting against ketoacidosis in insulin-dependent diabetes
10. Sustained insulin-induced remissions of juvenile diabetes by means of an external pancreas
11. Kinetics of human connecting peptide in normal and diabetic subjects
12. Determination of blood glucose using 4-aminophenazone as oxygen acceptor
13. Radioimmunological determination of human C-peptide in serum
14. Production of antisera to synthetic benzyloxycarbonyl-C-peptide of human proinsulin
15. Characterization of seven C-peptide antisera
16. The M-value, an index of blood-sugar control in diabetics
17. Prevalence of residual B-cell function in insulin-treated diabetics evaluated by the plasma C-peptide response to intravenous glucagon
18. Direct effect of insulin on the beta-cell function
19. Betacell function improved by supplementing basal insulin secretion in mild diabetes
20. Continous subcutaneous insulin infusion: improved blood glucose and intermediary-metabolite control in diabetics
21. Reduction to normal of plasma glucose in juvenile diabetes by subcutaneous administration of insulin with a portable infusion pump