Synthesis and Structure-Activity Relationship of Spiro[isochromanpiperidine] Analogues for Inhibition of Histamine Release. 1

Journal of Medicinal Chemistry

Volumn 24, Issue 2, 1981, Pages 194-198

  Yamato, Masatoshi ^a   Hashigaki, Kuniko ^a   Ikeda, Masao ^a   Ohtake, Hidetoshi ^a   Tasaka, Kenji ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 DEOXY 1 (3,4 DIHYDRO 2,4 DIOXO 1(2H) PYRIMIDINYL) N [2 (3 METHYL 3 NITROSOUREIDO)ETHYL] BETA D RIBOFURANURONAMIDE; 1 METHYL 3 NITROSOUREA; 1,2 DIDEOXY 1 (3,4 DIHYDRO 5 METHYL 2,4 DIOXO 1(2H) PYRIMIDINYL) N [2 (3 METHYL 3 NITROSOUREIDO)ETHYL] BETA D RIBOFURANURONAMIDE; 1,3 DICYCLOHEXYL 1 NITROSOUREA; CARMUSTINE; CHLOROZOTOCIN; N [2 (3 CYCLOHEXYL 1 NITROSOUREIDO)ETHYL] 1 DEOXY 1 (1,6 DIHYDRO 6 OXO 9H PURIN 9 YL) BETA D RIBOFURANAMIDE; N [2 (3 CYCLOHEXYL 1 NITROSOUREIDO)ETHYL] 1 DEOXY 1 (3,4 DIHYDRO 2,4 DIOXO 1(2H) PYRIMIDINYL) BETA D RIBOFURANURONAMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; DRUG ANALYSIS; DRUG COMPARISON; DRUG SCREENING; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HEP 2 CELL; HISTAMINE RELEASE; IN VITRO STUDY; NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; THEORETICAL STUDY; THIN LAYER CHROMATOGRAPHY; ULTRAVIOLET SPECTROPHOTOMETRY;

ANIMALS; CHEMISTRY; HISTAMINE RELEASE; MALE; MAST CELLS; PIPERIDINES; RATS; SPIRO COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0019367753     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00134a013     Document Type: Article

References (7)

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