Ammonia inhibits phagosome-lysosome fusion in macrophages

Nature

Volumn 286, Issue 5768, 1980, Pages 79-80

  Gordon, A H ^a   D'Arcy Hart, P ^a   Young, M R ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; AMMONIA;

ANIMAL; ARTICLE; DRUG EFFECT; INTRACELLULAR MEMBRANE; LYSOSOME; MACROPHAGE; MOUSE; PH; PHAGOCYTOSIS; PHYSIOLOGY; SACCHAROMYCES CEREVISIAE; ULTRASTRUCTURE;

AMINES; AMMONIA; ANIMAL; HYDROGEN-ION CONCENTRATION; INTRACELLULAR MEMBRANES; LYSOSOMES; MACROPHAGES; MICE; PHAGOCYTOSIS; SACCHAROMYCES CEREVISIAE;

EID: 0019315920     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/286079a0     Document Type: Article

References (17)

1. Armstrong, J. A. & D’Arcy Hart, P. J. exp. Med. 134, 713–740 (1971).
2. Jones, T. C, & Hirsch, J. G. J. exp. Med. 136, 1173–1194 (1972).
3. D’Arcy Hart, P. & Young, M. R. Nature 256, 47–49 (1975)
4. Expl Cell Rex. 114, 486–490 (1978)
5. Expl Cell Res. 118, 365–375 (1979)
6. Mononuclear Phagocytes-Functional Aspects (ed. van Furth, R.) (Martinius Nijhofl”. The Hague, in the press).
7. Goren, M. B., D’Arcy Hart, P., Young, M. R. & Armstrong, J. A. Proc. natn. Acad. Sci. U.S.A. 73, 2510–2514 (1976).
8. Geisow, M. J., Beaven, G. H., D’Arcy Hart, P. & Young, M. R. Expl Cell Res 126, 159–165 (1980).
9. Ratlcdgc, C. & Hall, M. J. J. Bact. 108, 312–319 (1971).
10. Hanks, J. H. & Wallace, R. E. Proc. Soc. exp. Biol. Med. 71, 196–200 (1949).
11. Long, E. R. Chemistry and Chemotherapy of Tuberculosis 3rd edn, 80–85 (Bailliere Tindall & Cox, London, 1958).
12. Ohkuma, S. & Poole, B. Proc. natn. Acad. Sci. U.S.A. 75, 3327–3331 (1978).
13. Seglen, O., Grinde, B. & Solheim, A. E. Eur. J. Biochem. 95, 215–225 (1979).
14. Rcijngoud, D-J., Oud, P. S., Kas, J. & Tagcr, J. M. Biochim. biophys. Acta 448, 290–302 (1976).
15. Wibo, M. & Poole, B. J. Cell Biol. 63, 430–440 (1974).
16. Reijngoud, D-J. & Tager, J. M. FEBS Lett. 64, 231–235 (1976).
17. Goldstein, J. L., Brunschedc, G. Y. & Brown, M. S. J. biol. Chem. 250, 7854–7862 (1975).