Treatment of Keratoacanthomas with Oral 13-cis-Retinoic Acid

New England Journal of Medicine

Volumn 303, Issue 10, 1980, Pages 560-562

  Haydey, Richard P ^a   Reed, Michael L ^a   Dzubow, Leonard M ^a   Shupack, Jerome L ^a  

^a Department of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RETINOIC ACID;

CASE REPORT; DRUG THERAPY; HISTOLOGY; KERATOACANTHOMA; ORAL DRUG ADMINISTRATION; THERAPY;

EID: 0019314074     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM198009043031005     Document Type: Article

References (31)

1. Baer R.L., Kopf A.W., eds. Yearbook of dermatology. Chicago: Year Book, 1963: 7-41.
2. Kopf A.W. Keratoacanthoma. In: Demis DJ, Dobson RL, Mcguire J, eds. Clinical dermatology. Vol. 4. New York: Harper & Row, 1979: 1-7.
3. Auerbach O., Stout A.P., Hammond E.C., Garfinkel L. Bronchial epithelium in former smokers. N Engl J Med. 1962; 267:119-125.
4. Saccomanno G., Saunders R.P., Klein M.G., Archer V.E., Brennan L. Cytology of the lung in reference to irritant, individual sensitivity and healing. Acta Cytol. 1970; 14:377-381.
5. Clamon G.H., Sporn M.B., Smith J.M., Saffiotti U. α- and β-Retinyl acetate reverse metaplasias of vitamin A deficiency in hamster trachea in organ culture. Nature. 1974; 250:64-66.
6. Hicks R.M. The mammalian urinary bladder: an accommodating organ. Biol Rev. 1975; 50:215-246.
7. Moore T. Effects of vitamin A deficiency in animals: pharmacology and toxicology of vitamin A. In: Sebrell WH Jr, Harris RS, eds. The vitamin. Vol. 1. New York: Academic Press, 1976; 245-56; 280-94.
8. Nettesheim P., Williams M.L. The influence of vitamin A on the susceptibility of the rat lung to 3-methylcholanthrene. Int J Cancer. 1976; 17:351-357.
9. Cohen S.M., Wittenberg J.F., Bryan G.T. Effect of avitaminosis A and hypervitaminosis A on urinary bladder carcinogenicity of N-[4-(5-Nitro-2-furyl)-2-Thiazolyl]formamide. Cancer Res. 1976: 36:2334-2339.
10. Newberne P.M., Rogers A.E. Rat colon carcinomas associated with aflatoxin and marginal vitamin A. J Natl Cancer Inst. 1973; 50:439-448.
11. Bjelke E. Dietary vitamin A and human lung cancer. Int J Cancer. 1975; 15:561-565.
12. Lasnitzki I. Reversal of methylcholanthrene-induced changes in mouse prostates in vitro by retinoic acid and its analogues. Br J Cancer. 1976; 34:239-248.
13. Mayer H., Bollag W., Hänni R., Ruëgg R. Retinoids, a new class of compounds with prophylactic and therapeutic activities in oncology and dermatology. Experientia. 1978; 34:1105-1119.
14. Saffiotti U., Montesano R., Sellakumar A.R., Borg S.A. Experimental cancer of lung: inhibition by vitamin A of the induction of tracheobronchial squamous metaplasia and squamous cell tumors. Cancer. 1967; 20:857-864.
15. Moon R.C., Thompson H.J., Becci P.J., et al. N-(4-Hydroxyphenyl)retinamide, a new retinoid for prevention of breast cancer in the rat. Cancer Res. 1979; 39:1339-1346.
16. Sporn M.B., Squire R.A., Brown C.C., Smith J.M., Wenk M.L., Springer S. 13-cis retinoic acid: inhibitor of bladder carcinogenesis in the rat. Science. 1977; 195:487-489.
17. Chu E.W., Malmgren R.A. An inhibitory effect of vitamin A on the induction of tumors of forestomach and cervix in the Syrian hamster by carcinogenic polycyclic hydrocarbons. Cancer Res. 1965; 25:884-895.
18. Chytil F., Ong D.E. Cellular retinol and retinoic acid-binding proteins in vitamin A action. Fed Proc. 1979; 38:2510-2514.
19. Ross AC, Goodman D. Intracellular binding proteins for retinol and retinoic acid: comparison with each other and with serum retinolbinding protein. Fed Proc. 1979; 38:2515-2518.
20. Sani B.P. Localization of retinoic acid-binding protein in nuclei. Biochem Biophys Res Commun. 1977; 75:7-12.
21. Prutkin L., Bogart B. The uptake of labeled vitamin A acid in keratoacanthoma: an electron microscopic radioautography study. J Invest Dermatol. 1970; 55:249-255.
22. Harris C.C., Silverman T., Smith J.M., Jackson F., Boren H.G. Proliferation of tracheal epithelial cells in normal and vitamin A-deficient Syrian golden hamsters. J Natl Cancer Inst. 1973; 51:1059-1062.
23. Tsai C.H., Chytil F. Effect of vitamin A deficiency on RNA synthesis in isolated rat liver nuclei. Life Sci. 1978; 23:1461-1472.
24. Haddox M.K., Russell D.H. Cell cycle-specific locus of vitamin A inhibition of growth. Cancer Res. 1979; 39:2476-2480.
25. Jänne J., Pösö H., Raina A. Polyamines in rapid growth and cancer. Biochim Biophys Acta. 1978; 473:241-293.
26. Todaro G.J., De Larco J.E., Sporn M.B. Retinoids block phenotypic cell transformation produced by sarcoma growth factor. Nature. 1978; 276:272-274.
27. Wolf G., Kiorpes T.C., Masushige S., Schreiber J.B., Smith M.J., Anderson R.S. Recent evidence for the participation of vitamin A in glycoprotein synthesis. Fed Proc. 1979; 38:2540-2543.
28. Dion L.D., Blalock J.E., Gifford G.E. Retinoic acid and the restoration of anchorage dependent growth to transformed mammalian cells. Exp Cell Res. 1978; 117:15-22.
29. Dennert G., Lotan R. Effects of retinoic acid on the immune system: stimulation of T killer cell induction. Eur J Immunol. 1978; 8:23-29.
30. Micksche M., Cerni C., Kokron O., Titscher R., Wrba H. Stimulation of immune response in lung cancer patients by vitamin A therapy. Oncology. 1977; 34:234-238.
31. Silverberg E., Holleb A.I. Major trends in cancer: 25 year survey. CA. 1975; 25:2-7.