A New Instrument for the Simultaneous Measurement of Total Hemoglobin; % Oxyhemoglobin, % Carboxyhemoglobin, % Methemoglobin, and Oxygen Content in Whole Blood

IEEE Transactions on Biomedical Engineering

Volumn BME-27, Issue 3, 1980, Pages 132-138

  Brown, Leslie J ^a,b  

^a INOVA DIAGNOSTICS INC   (United States)

^b Teledyne TAC ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MATERIALS - BLOOD; COMPUTERS, DIGITAL - SPECIAL PURPOSE APPLICATION; COMPUTERS, MINIATURE - APPLICATIONS; SPECTROPHOTOMETERS;

HEMOGLOBIN; MICROCOMPUTERS; OXIMETERS;

BIOMEDICAL EQUIPMENT;

CARBOXYHEMOGLOBIN; HEMOGLOBIN; METHEMOGLOBIN; OXYHEMOGLOBIN;

BLOOD AND HEMOPOIETIC SYSTEM; HUMAN CELL; METHODOLOGY; OXYGEN BLOOD LEVEL;

CARBON DIOXIDE; CARBOXYHEMOGLOBIN; ELECTRONICS, MEDICAL; HEMOGLOBINS; HUMAN; METHEMOGLOBIN; OXIMETRY; OXYGEN; OXYHEMOGLOBINS; RHEOLOGY; SPECTROPHOTOMETRY;

EID: 0019230982     PISSN: 00189294     EISSN: 15582531     Source Type: Journal    
DOI: 10.1109/TBME.1980.326613     Document Type: Article

References (16)

1. R. F. Cobuin, “Endogenous carbon monoxide production,” New Eng. J. Med., vol. 282, pp. 207–209, 1970.
2. M. Kiese, Methemoglobinemia: A Comprehensive Treatise. Cleveland, OH: CRC, 1979, ch. 1–7.
3. W. Falholt, “Blood oxygen saturation determined spectropho-tometrically,” Scand. J. Clin. Lab. Investigation, vol. 15, pp. 67–72, 1963.
4. A. Ramieri, Jr., P. Jatlow, and D. Seligson, “A new method for rapid determination of carboxyhemoglobin by use of double-wavelength spectrophotometry,” Clin. Chem., vol. 20, pp. 278–281, 1974.
5. A. L. Malenfant, S. R. Gambino, A. J. Waraksa, and E. I. Roe, “Spectrophotometric determination of hemoglobin concentration and % oxyhemoglobin and % carboxyhemoglobin saturation,” presented at the Amer. Ass. Clin. Chem., 20th Nat. Meeting, Aug. 19, 1968.
6. S. R. Gambino, Hemoglobinometry. Chicago, IL: Amer. Ass. Clin. Pathologists, 1967, pp. 35–46.
7. D. D. Van Slyke and J. M. Neill, “The determination of gases in blood and other solutions by vacuum extraction and mano-metric measurement,” Int. J. Biol. Chem., vol. 61, pp. 523–557, 1924.
8. H. A. Cortison, F. L. Rodkey, and J. D. O'Neal, “Determination of carbon monoxide in blood by gas chromatography,” Clin. Chem., vol. 14, pp. 162–171, 1968.
9. LEX-O2-CON, Lexington Instr. Corp., 241 Crescent St., Waltham, MA 02154.
10. K. A. Evelyn and H. T. Malloy, “Microdetermination of oxyhemoglobin, methemoglobin, and sulfhemoglobin in a single sample of blood,” J. Biol. Chem., vol. 126, pp. 655–662, 1938.
11. F. L. Rodkey and J. D. O'Neal, “Effects of carboxyhemoglobin on the determination of methemoglobin in blood,” Biochem. Med., vol. 9, pp. 261–270, 1974.
12. O. Siggard-Andersen, B. Nørgaard-Pedersen, and J. Rem, “Hemoglobin pigments. Spectrophotometric determination of oxy-, carboxy-, met-, and sulfhemoglobin in capillary blood,” Clinica Chimica Acta, vol. 42, pp. 85–100, 1972.
13. O. W. Van Assendelft, Spectrophotometry of Haemoglobin Derivatives. Assen, The Netherlands: Thomas, 1970, pp. 55–65.
14. Intel 4004 Microcomputer, Intel Corp., 3065 Bowers Ave., Santa Clara, CA 95051.
15. IL 813, 713, or 513 Blood Gas Analyzer, Instrumentation Lab. Inc., 113 Hartwell Ave., Lexington, MA 02173.
16. M. J. Edwards and R. J. Martin, “Mixing technique for the oxygen-hemoglobin equilibrium and Bohr effect,” J. Appl. Physiol., vol. 21, pp. 1898–1902, 1966.