An enantiomeric interaction in the metabolism and tumorigenicity of (+)- and (-)-benzo[a]pyrene 7,8-oxide

Journal of Biological Chemistry

Volumn 255, Issue 19, 1980, Pages 9067-9074

  Levin, W ^a   Buening, M K ^a   Wood, A W ^a   Chang, R L ^b   Kedzierski, B ^b   Thakker, D R ^b   Boyd, D R ^b   Gadaginamath, G S ^b   Armstrong, R N ^b   Yagi, H ^b   Karle, J M ^b   Slaga, T J ^b   Jerina, D M ^b   Conney, A H ^b  

^a HOFFMANN LA ROCHE INC   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

7,8 DIHYDRO 7,8 DIHYDROXYBENZO[A]PYRENE; BENZO[A]PYRENE 7,8 OXIDE; BENZO[A]PYRENE 7,8 OXIDE H 3; EPOXIDE HYDROLASE; PHENANTHRENE EPOXIDE H 3; RADIOISOTOPE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CHEMICAL CARCINOGENESIS; DRUG METABOLISM; DRUG POTENTIATION; ENANTIOMER; IN VITRO STUDY; LIVER; PHARMACOKINETICS; PRELIMINARY COMMUNICATION; RAT;

ANIMALS; BENZOPYRENES; CARCINOGENS; CRICETINAE; EPOXIDE HYDROLASES; FEMALE; HUMANS; KINETICS; MALE; MICE; MICROSOMES, LIVER; NEOPLASMS, EXPERIMENTAL; PHENOBARBITAL; RABBITS; RATS; SKIN NEOPLASMS; SPECIES SPECIFICITY; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA; CAVIA PORCELLUS; CRICETINAE; ORYCTOLAGUS CUNICULUS; SUS SCROFA;

EID: 0019198422     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (0)