Correlation between Serum IgG-2 Concentrations and the Antibody Response to Bacterial Polysaccharide Antigens

New England Journal of Medicine

Volumn 303, Issue 4, 1980, Pages 178-182

  Siber, George R ^a   Schur, Peter H ^a   Aisenberg, Alan C ^a   Weitzman, Sigmund A ^a   Schiffman, Gerald ^a  

^a SUNY DOWNSTATE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM ANTIBODY; IMMUNOGLOBULIN G2; VIRUS ANTIBODY;

ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; CHEMOTHERAPY; HAEMOPHILUS INFLUENZAE; HODGKIN DISEASE; IMMUNOCOMPETENCE; IMMUNOGLOBULIN BLOOD LEVEL; IRRADIATION; LYMPHATIC SYSTEM; MAJOR CLINICAL STUDY; STREPTOCOCCUS PNEUMONIAE;

EID: 0018950766     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM198007243030402     Document Type: Article

References (21)

1. Siber G.R., Weitzman S.A., Aisenberg A.C., Weinstein H.J., Schiffman G. Impaired antibody response to pneumococcal vaccine after treatment for Hodgkin#x0027;s disease. N Engl J Med. 1978; 299:442-448.
2. Yount W.J., Dorner M.M., Kunkel H.G., Kabat E.A. Studies on human antibodies. VI. Selective variations in subgroup composition and genetic markers. J Exp Med. 1968; 127:633-646.
3. Riesen W.F., Skvaril F., Braun D.G. Natural infection of man with group A streptococci: levels; restriction in class, subclass, and type; and clonal appearance of polysaccharide-group-specific antibodies. Scand J Immunol. 1976; 5:383-390.
4. Alper C.A. Plasma protein measurements as a diagnostic aid. N Engl J Med. 1974; 291:287-290.
5. Schur P.H., Rosen F., Norman M.E. Immunoglobulin subclasses in normal children. Pediatr Res. 1979; 13:181-183.
6. O#x0027;Reilly R.J., Anderson P., Ingram D.L., Peter G., Smith D.H. Circulating polyribophosphate in Hemophilus influenzae, type b meningitis: correlation with clinical course and antibody response. J Clin Invest. 1975; 56:1012-1022.
7. Noble G.R., Kay H.S., Yarbrough W.B., et al. Measurement of hemagglutination-inhibiting antibody to influenza virus in the 1976 Influenza Vaccine Program: methods and test reproducibility. J Infect Dis. 1977; 136: Suppl:S429-34.
8. Yount W.J., Hong R., Seligmann M., Good R., Kunkel H.G. Imbalances of gamma globulin subgroups and gene defects in patients with primary hypogammaglobulinemia. J Clin Invest. 1970; 49:1957-1966.
9. Hancock B.W., Bruce L., Dunsmore I.R., Ward A.M., Richmond J. Follow-up studies on the immune status of patients with Hodgkin#x0027;s disease after splenectomy and treatment, in relapse and remission. Br J Cancer. 1977; 36:347-354.
10. Pandey J.P., Fudenberg H.H., Virella G., Kyong C.U., Loadholt C.B., Galbraith R.M. Association between immunoglobulin allotypes and immune responses to Haemophilus influenzae and meningococcus polysaccharides. Lancet. 1979; 1:190-192.
11. Sell S.H., Schiffman G., Vaughn W.K., Wright P.F. Clinical trial of octavalent pneumococcal polysaccharide vaccine in infants — a preliminary report. Antimicrob Agents Chemother. 1978; abstract 17.
12. Gold R., Lepow M.L., Goldschneider I., Draper T.L., Gotschlich E.C. Clinical evaluation of group A and group C meningococcal polysaccharide vaccines in infants. J Clin Invest. 1975; 56:1536-1547.
13. Robbins J.B., Schneerson R., Argaman M., Handzel Z.T. Haemophilus influenzae type b: disease and immunity in humans. Ann Intern Med. 1973; 78:259-269.
14. Morell A., Skvaril F., Hitzig W.H., Barandun S. IgG subclasses: development of the serum concentrations in “normal” infants and children. J Pediatr. 1972; 80:960-964.
15. Oxelius V.-A. Chronic infections in a family with hereditary deficiency of IgG2 and IgG4. Clin Exp Immunol. 1974; 17:19-27.
16. Schur P.H., Borel H., Gelfand E.W., Alper C.A., Rosen F.S. Selective gamma-G deficiencies in patients with recurrent pyogenic infections. N Engl J Med. 1970; 283:631-634.
17. Rothbach C., Nagel J., Rabin B., Fireman P. Antibody deficiency with normal immunoglobulins. J Pediatr. 1979; 94:250-253.
18. Herrod H.G., Sullivan J.L., Buckley R.H., Schiffman G., Sampson H.A., Wedgwood R.J. Antibody deficiency with near normal immunoglobulins. J Allergy Clin Immunol. 1979; 63:188.
19. Perlmutter R.M., Hansburg D., Briles D.E., Nicolotti R.A., Davie J.M. Subclass restriction of murine anti-carbohydrate antibodies. J Immunol. 1978; 121:566-572.
20. Heidelberger M., DiLapi M.M., Siegel M., Walter A.W. Persistence of antibodies in human subjects injected with pneumococcal polysaccharides. J Immunol. 1950; 65:535-541.
21. Anderson P., Peter G., Johnston R.B. Jr., Wetterlow L.H., Smith D.H. Immunization of humans with polyribophosphate, the capsular antigen of Hemophilus influenzae, type b. J Clin Invest. 1972; 51:39-44.