Dopaminergic prodrugs: Brain concentrations and neurochemical effects of 5,6- and 6,7-ADTN after administration as dibenzoyl esters

European Journal of Pharmacology

Volumn 61, Issue 1, 1980, Pages 7-15

  Westerink, Ben H C ^a   Dijkstra, Durk ^a   Feenstra, Matthijs G P ^a   Grol, Cor J ^a   Horn, Alan S ^a   Rollema, Hans ^a   Wirix, Els ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

2 Amino 5,6 dihydroxytetralin derivatives; 2 Amino 6,7 dihydroxytetralin derivatives; Dopamine; Dopamine agonist; Homovanillic acid

Indexed keywords

2 AMINO 5,6 DIHYDROXYTETRALIN DERIVATIVE; 2 AMINO 6,7 DIHYDROXYTETRALIN DERIVATIVE; DOPAMINE; HOMOVANILLIC ACID; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR; CENTRAL NERVOUS SYSTEM; CORPUS STRIATUM; DOPAMINE BRAIN LEVEL; DRUG BRAIN LEVEL; DRUG COMPARISON; DRUG METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOMOVANILLIC ACID BRAIN LEVEL; INTRAPERITONEAL DRUG ADMINISTRATION; LIQUID CHROMATOGRAPHY; RAT;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN CHEMISTRY; FEMALE; HOMOVANILLIC ACID; INJECTIONS, INTRAPERITONEAL; NAPHTHALENES; NAPHTHOLS; RATS; TETRAHYDRONAPHTHALENES;

EID: 0018898101     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(80)90376-3     Document Type: Article

References (20)

1. Evidence for dopamine receptor stimulation by apomorphine
2. Cerebral dopamine agonist properties of some 2-aminotetralin derivatives after peripheral and intracerebral administration
3. 3H-haloperidol to neuroleptic receptors in the rat striatum
4. Differential activation by some 2-aminotetralin derivatives of the receptor mechanism in the nucleus accumbens of rat which mediate hyperactivity and stereotyped biting
5. Effect of dihydroxy-2-aminotetralin derivatives on dopamine metabolism in the rat striatum
6. Facile syntheses of potent dopaminergic agonists and their effects on neurotransmitter release
7. A new dopaminergic prodrug
8. Liquid chromatographic analysis of catecholamines routine assay for regional brain mapping
9. Synthesis and pharmacology of some 2-aminotetralins. Dopamine receptor agonists
10. Effects of dopamine-like drugs on rat striatal adenyl cyclase have implication for CNS dopamine receptor topography
11. Optimized isocratic conditions for analysis of catecholamines by high-performance reversed-phase paired-ion chromatography with amperometric detection
12. Correlation between neuroleptic induced supression of stereotyped behaviour and HVA levels in the rat brain
13. Decrease in HVA as evidence for dopaminergic receptor stimulation by apomorphine in the neostriatum of the rat
14. Brain receptirs for dopamine and neuroleptics
15. Determination of urinary normetanephrine, metanephrine, and 3-methoxytyramine by liquid chromatography, with amperometric detection
16. Schizophrenic symptoms improve with apomorphine
17. Turnover of acid dopamine metabolites in striatal and mesolimbic tissue of the rat brain
18. Rapid concurrent fluorimetric assay of noradrenaline, dopamine, 3,4-dihydroxyphenylacetic acid, homovanillic acid and 3-methoxytyramine in milligram amounts of nervous tissue after isolation on Sephadex G 10
19. Biochemical and pharmacological studies on dopamine receptors
20. Dopamine receptors in rat striatum and nucleus accumbens: conformational studies using rigid analogues of dopamine