Fetal Hydantoin Syndrome, Neuroblastoma, and Hemorrhagic Disease in a Neonate

JAMA: The Journal of the American Medical Association

Volumn 244, Issue 13, 1980, Pages 1464-1465

  Allen, Robert W ^a   Ogden, Bruce ^a   Bentley, Frank L ^a   Jung, August L ^a  

^a PRIMARY CHILDREN'S MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN; PHENOBARBITAL; PHENYTOIN; PHYTOMENADIONE; PRIMIDONE;

ADVERSE DRUG REACTION; BLEEDING; BLEEDING DISORDER; BLEEDING TENDENCY; CENTRAL NERVOUS SYSTEM; FETAL HYDANTOIN SYNDROME; FETUS; HEREDITY; MATERNAL EPILEPSY; NERVOUS SYSTEM; NEURAL CREST; NEUROBLASTOMA; NEWBORN; ORAL DRUG ADMINISTRATION; PREGNANCY; PRENATAL DRUG EXPOSURE; TERATOGENESIS;

ABNORMALITIES, DRUG-INDUCED; ABNORMALITIES, MULTIPLE; CASE REPORT; EPILEPSY; FEMALE; HEMORRHAGIC DISEASE OF NEWBORN; HUMAN; HYDANTOINS; INFANT, NEWBORN; MALE; MATERNAL-FETAL EXCHANGE; NEUROBLASTOMA; PHENYTOIN; PLACENTA; PREGNANCY; PREGNANCY COMPLICATIONS; SYNDROME;

EID: 0018869856     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.1980.03310130042027     Document Type: Article

References (11)

1. Seeler RA, Israel JN, Royal JE, et al: Ganglioneuroblastoma and fetal hydantoin-alcohol syndromes. Pediatrics 63:524-527, 1979.
2. Pendergrass RW, Hanson JW: Fetal hydantoin syndrome and neuroblastoma. Lancet 2:150, 1976.
3. Sherman S, Roizen N: Fetal hydantoin syndrome and neuroblastoma. Lancet 2:517, 1976.
4. Bleyer WP, Skinner AL: Fatal neonatal hemorrhage after maternal anticonvulsant therapy. JAMA 235:626-627, 1976.
5. Mountain KR, Hirsh J, Gallus AS: Neonatal coagulation defect due to anticonvulsant drug treatment in pregnancy. Lancet 1:265-268, 1970.
6. Smith DW: Recognizable Patterns of Human Malformation, ed 2. Philadelphia, WB Saunders Co, 1976, pp 346-347.
7. Hanson JW, Myrianthopoulos NC, Harvey MAS, et al: Risks to the offspring of women treated with hydantoin anticonvulsant and emphasis on the fetal hydantoin syndrome. J Pediatr 89:662-668, 1976.
8. Pochedly C: Neuroblastoma. Acton, Mass, Publishing Sciences Group Inc, 1976, p 23.
9. Solomon GE, Hilgartner MW, Kutt H: Coagulation defects caused by diphenylhydantoin. Neurology 22:1165-1171, 1972.
10. McMillan CW, Gaudry CL, Holemans R: Coagulation defects and metastatic neuroblastoma. J Pediatr 73:347-350, 1968.
11. Zimmerman HJ: Hepatotoxicity. New York, Appleton-Century-Crofts, 1978, pp 408-409.