Successful treatment of inorganic mercury neurotoxicity with N-acetyl-penicillamine despite an adverse reaction

Neurology

Volumn 30, Issue 9, 1980, Pages 1000-1001

  Markowitz, Larry ^a   Schaumburg, Herbert H ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHISTAMINIC AGENT; DIPHENHYDRAMINE; MERCURY; N ACETYLPENICILLAMINE;

ADVERSE DRUG REACTION; CASE REPORT; CENTRAL NERVOUS SYSTEM; DRUG THERAPY; FACE EDEMA; INORGANIC MERCURY; INTOXICATION; NERVOUS SYSTEM; NEUROTOXICITY; PERIPHERAL NERVOUS SYSTEM; PRURITUS; STOMACH PAIN; THERAPY; TREMOR;

AGED; CASE REPORT; HUMAN; MALE; MERCURY POISONING; OCCUPATIONAL DISEASES; PENICILLAMINE; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0018848785     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/wnl.30.9.1000     Document Type: Article

References (3)

1. Aposhian HV, Aposhian MM: N-acetyl-D, L-penicillamine, a new oral protective agent against the lethal effects of mercuric chloride. J Pharmacol Exp Ther 126: 131-135, 1959
2. Kark RAP, Poskanzer DC, Bullock JD, et al: Mercury poisoning and its treatment with N-acetyl-D, L-penicillamine. N Engl J Med 285: 10-16, 1971
3. Kark RAP: Clinical and neurochemical aspects of inorganic mercury intoxication. In Vinken PJ, Bruyn GW (Editors): Handbook of Clinical Neurology. Amsterdam, North Holland Publishing Co, 1979, vol 36, chap 6, pp 183-184