Structure-Antitubulin Activity Relationships in Steganacin Congeners and Analogs. Inhibition of Tubulin Polymerization in Vitro by (±)-Isodeoxypodophyllotoxin

Journal of Medicinal Chemistry

Volumn 23, Issue 5, 1980, Pages 546-549

  Zavala, Flora ^a   Guenard, Daniel ^a   Robin, Jean Pierre ^b   Brown, Eric ^b  

^a CNRS   (France)

^b Faculti des Sciences ^*  (France)

Author keywords

[No Author keywords available]

Indexed keywords

COLCHICINE; PODOPHYLLOTOXIN; RADIOISOTOPE; STEGANONE; TUBULIN;

COLCHICINE H 3; DRUG ANALYSIS; DRUG COMPARISON; DRUG INTERACTION; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; ISODEOXYPODOPHYLLOTOXIN; MICROTUBULE; POLYMERIZATION; STEGANACIN; STEGANACIN DERIVATIVE; STEGANE DERIVATIVE; STEGANOL; STRUCTURE ACTIVITY RELATION; THEORETICAL STUDY; TURBIDIMETRY;

COLCHICINE; DEPRESSION, CHEMICAL; KINETICS; PODOPHYLLOTOXIN; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN;

EID: 0018841140     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00179a014     Document Type: Article

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