The effect of hypothyroidism on growth, serum growth hormone, the growth hormone-dependent somatomedin, insulin-like growth factor, and its carrier protein in rats

Endocrinology

Volumn 104, Issue 4, 1979, Pages 1107-1111

  Burstein, Philip J ^a   Draznin, Boris ^a   Johnson, Carolyn J ^a   Schalch, Don S ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; PROPYLTHIOURACIL; SOMATOMEDIN;

ANIMAL EXPERIMENT; ENDOCRINE SYSTEM; GROWTH; GROWTH HORMONE BLOOD LEVEL; GROWTH RETARDATION; HORMONE PROTEIN COMPLEX; HYPOTHYROIDISM; PROTEIN BINDING; RAT;

AGING; ANIMAL; BODY WEIGHT; CARRIER PROTEINS; FEMALE; GROWTH DISORDERS; GROWTH HORMONE; HYPOTHYROIDISM; MALE; NONSUPPRESSIBLE INSULIN-LIKE ACTIVITY; PROPYLTHIOURACIL; RATS; SOMATOMEDINS; SUPPORT, U.S. GOV'T, P.H.S.; THYROXINE;

EID: 0018779390     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/endo-104-4-1107     Document Type: Article

References (39)

1. Wilkins, J. N., S. E. Mayer, and W. P. Van der Laan, The effects of hypothyroidism and 2, 4-dinitrophenol on growth hormone synthesis, Endocrinology 95: 1259, 1974.
2. Hervas, F., G. Morreale de Escobar, and F. Escobar del Rey, Rapid effects of single small doses of L-thyroxine and triiodo-L-thyronine on growth hormone as studied in the rat by radioimmunoassay, Endocrinology 97: 91, 1975.
3. Rinderknecht, E., and R. E. Humbel, Amino-terminal sequence of two polypeptides from human serum with nonsuppressible insulinlike and cell growth promoting activities: evidence for structural homology with insulin B-chain, Proc Natl Acad Sci 73: 4379, 1976.
4. Froesch, E. R., J. Zapf, C. Meuli, M. Màder, M. Waldvogel, A. Kaufmann, and B. Morell, Biologic properties of NSILA-S, Adv Metab Disord 8: 211, 1975.
5. Hall, K., K. Takano, L. Fryklund, and H. Sievertsson, Somatomedins, Adv Metab Disord 8: 19, 1975.
6. Van Wyk, J. J., L. E. Underwood, J. B. Baseman, R. L. Hintz, D. R. Clemmons, and R. N. Marshall, Explorations of the insulin-like and growth-promoting properties of somatomedin by membrane receptor assays, Adv Metab Disord 8: 128, 1975.
7. Oeltz, O., E. R. Froesch, H. F. Bunzli, R. E. Humbel, and W. J. Ritschard, Insulin-like activity, In Steiner, D. R., and N. Freinkel (eds.), Handbook of Physiology, vol. 1, Williams & Wilkins, Baltimore, 1972, p. 685.
8. Schlumpf, U., R. Heimann, J. Zapf, and E. R. Froesch, Non-sup-pressible insulin-like activity in serum extracts of normal subjects, acromegalics, and pituitary dwarfs, Acta Endocrinol (Kbh) 81: 28, 1976.
9. Zingg, A. E., and E. R. Froesch, Effects of partially purified preparations with non-suppressible insulin-like activity (NSILA-S) on sulfate incorporation into the rat and chicken cartilage, Diabeto-logia 9: 472, 1973.
10. Moses, A. C., S. P. Nissley, K. L. Cohen, and M. M. Rechler, Specific binding of a somatomedin-like polypeptide in rat serum depends on growth hormone, Nature 263: 137, 1976.
11. Zapf, J., M. Waldvogel, and E. R. Froesch, Binding of nonsuppressible insulin-like activity to human serum. Evidence for a carrier protein, Arch Biochem Biophys 168: 638, 1975.
12. Heinrich, U. E., D. S. Schalch, J. G. Koch, and C. J. Johnson, Nonsuppressible insulin-like activity (NSILA). II. Regulation of serum concentrations by growth hormone and insulin, J Clin Endocrinol Metab 46: 672, 1978.
13. Kaufmann, U., J. Zapf, and E. R. Froesch, Growth-hormone dependence of nonsuppressible insulin-like activity (NSILA) and of NSILA-carrier protein in rats, Acta Endocrinol (Kbh) 87: 716, 1978.
14. Hintz, R. L., and F. Liu, Demonstration of specific plasma protein binding sites for somatomedin, J Clin Endocrinol Metab 45: 988, 1977.
15. Chochinov, R. H., and W. H. Daughaday, Current concepts of somatomedin and other biologically related growth factors, Diabetes 25: 994, 1976.
16. Froesch, E. R., J. Zapf, T. K. Audhya, E. Ben-Porath, B. J. Segen, and K. D. Gibson, Non-suppressible insulin-like activity and thyroid hormones: major pituitary-dependent sulfation factors for chick embryo cartilage, Proc Natl Acad Sci 73: 2904, 1976.
17. Audhya, T. K., and K. D. Gibson, Enhancement of somatomedin titers of normal and hypopituitary sera by addition of L-triiodothy-ronine in vitro at physiological concentrations, Proc Natl Acad Sci 72: 604, 1975.
18. Gespard, S. T., R. Wondergem, and H. M. Klitgaard, Effect of growth hormone and thyroxine on serum somatomedin and growth, Fed Proc 34: 272, 1975 (Abstract).
19. Rechler, M. M., J. Zapf, S. P. Nissley, E. R. Froesch, A. C. Moses, J. M. Podskalny, E. Schilling, and L. Fryklund, Cross-reactivity of MSA (multiplication stimulating activity) and NSILA (nonsup-pressible insulin-like activity) I and II in competitive binding assays, Clin Res 25: 300, 1977 (Abstract).
20. Moses, A. C., S. P. Nissley, M. M. Rechler, and P. A. Short, Demonstration by radioimmunoassay of multiplication stimulating activity (MSA) in rat serum, Program of the 60th Meeting of The Endocrine Society, Miami, FL, 1978 (Abstract 30).
21. Burstein, P. J., D. S. Schalch, U. E. Heinrich, and C. J. Johnson, The effects of hypothyroidism on somatomedin IGF (insulin-like growth factor), Clin Res 26: 411, 1978 (Abstract).
22. Wilber, J. F., and R. D. Utiger, Immunoassay studies of thyrotropin in rat pituitary glands and serum, Endocrinology 81: 145, 1967.
23. Daughaday, W. H., J. N. Heins, L. Srivastava, and C. Hammer, Sulfation factor: studies of its removal from plasma and metabolic fate in cartilage, J Lab Clin Med 72: 803, 1968.
24. Schalch, D. S., U. E. Heinrich, J. G. Koch, C. J. Johnson, and R. J. Schlueter, Nonsuppressible insulin-like activity (NSILA). I. Development of a new sensitive competitive protein-binding assay for determination of serum levels, J Clin Endocrinol Metab 46: 664, 1978.
25. Schalch, D. S., U. E. Heinrich, B. Draznin, C. J. Johnson, and L. L. Miller, Role of the liver in regulating somatomedin activity: hormonal effects on the synthesis and release of insulin-like growth factor and its carrier protein by the isolated perfused rat liver, Endocrinology 104: 1143, 1979.
26. Zapf, J., E. Schoenle, and E. R. Froesch, Insulin-like growth factors I and II: some biological actions and receptor binding characteristics of two purified constituents of nonsuppressible insulin-like activity of human serum, Eur J Biochem 87: 285, 1978.
27. Schalch, D. S., and S. Reichlin, Plasma growth hormone concentration in the rat determined by radioimmunoassay: influence of sex, pregnancy, lactation, anesthesia, hypophysectomy and extrasellar pituitary transplants, Endocrinology 79: 275, 1966.
28. Tato, L., M. V. L. Du Caju, C. Prevot, and R. Rappaport, Early variations of plasma somatomedin activity in the newborn, J Clin Endocrinol Metab 40: 534, 1975.
29. D’Ercole, A. J., B. D. Foushee, and L. E. Underwood, Somatomedin C receptor ontogeny and levels in porcine fetal and human cord serum, J Clin Endocrinol Metab 43: 1069, 1976.
30. Giordano, G., E. Foppiani, F. Minuto, and D. Perroni, Growth hormone and somatomedin behavior in the newborn, Acta Endocrinol (Kbh) 81: 449, 1976.
31. Gluckman, P. D., and M. W. Brinsmead, Somatomedin in cord blood: relationship to gestational age and birth size, J Clin Endocrinol Metab 43: 1378, 1976.
32. Hintz, R. L., and J. M. Seeds, Somatomedin and growth hormone in the newborn, Am J Dis Child 131: 1249, 1977.
33. Svan, H., K. Hall, M. Ritzen, K. Takano, and A. Skottner, Somatomedin A and B in serum from neonates, their mothers and cord blood, Acta Endocrinol (Kbh) 85: 636, 1977.
34. Heinrich, U. E., J. G. Koch, C. J. Johnson, R. J. Schlueter, and D. S. Schalch, Nonsuppressible insulin like activity (NSILA-S): plasma levels and their relationship to growth hormone and NSILA-S carrier protein concentrations, Program of the 58th Meeting of The Endocrine Society, San Francisco, CA, 1976 (Abstract 155).
35. Cohen, K. L., and S. P. Nissley, The serum half-life of somatomedin activity: evidence for growth hormone dependence, Acta Endocrinol (Kbh) 83: 243, 1977.
36. Saunders, A., L. C. Terry, J. Audet, P. Brazeau, and J. B. Martin, Dynamic studies of growth hormone and prolactin secretion in the female rat, Neuroendocrinology 21: 193, 1976.
37. Shaffer Tannenbaum, G., J. B. Martin, and E. Colle, Ultradian growth hormone rhythm in the rat: effects of feeding, hyperglycemia, and insulin-induced hypoglycemia, Endocrinology 99: 720, 1976.
38. Cocchi, D., I. Gil-Ad, A. E. Panerai, V. Locatelli, and E. E. Muller, Circadian variations in plasma growth hormone and prolactin in the infant rat: comparison with the adult pattern, Life Sci 19: 825, 1976.
39. Schalch, D. S., and S. Reichlin, Stress and growth hormone release, In Pecile, A., and E. Muller (eds.) Growth Hormone, Excerpta Medica Foundation, Amsterdam, 1968, p. 211.