β-Adrenoceptor Studies. 5.1NMR and IR Spectroscopic Analysis of the Conformation of the Hydrohalide Salts of β-Adrenoceptor-Blocking Aryloxypropanolamines. Evidence for a Seven-Membered Ring Structure with Participation of Two Hydrogen Bonds

Journal of Medicinal Chemistry

Volumn 22, Issue 4, 1979, Pages 441-449

  Zaagsma, Johan ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR; DRUG RECEPTOR; ISOPRENALINE; TOLIPROLOL;

2 ISOPROPYLAMINO 3 (3 METHYLPHENOXY) 1 PROPANOL; ANIMAL EXPERIMENT; ARYLOXYPROPANOLAMINE DERIVATIVE; DRUG ANALYSIS; DRUG ANTAGONISM; DRUG COMPARISON; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; GUINEA PIG; HEART; HEART ATRIUM; IN VITRO STUDY; INFRARED SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; REGIONAL PERFUSION; RESPIRATORY SYSTEM; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; THEORETICAL STUDY; TOLIPROLOL DERIVATIVE; TRACHEA;

ADRENERGIC BETA-ANTAGONISTS; ANIMAL; GUINEA PIGS; HEART; HYDROGEN BONDING; IN VITRO; ISOPROTERENOL; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; PROPANOLAMINES; SPECTROPHOTOMETRY, INFRARED; STRUCTURE-ACTIVITY RELATIONSHIP; TRACHEA;

EID: 0018722568     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00190a017     Document Type: Article

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