2ʹ-O-Acyl-6-thioinosine Cyclic 3ʹ,5ʹ-Phosphates as Prodrugs of Thioinosinic Acid

Journal of Medicinal Chemistry

Volumn 22, Issue 7, 1979, Pages 811-815

  Meyer, Rich B ^a   Stone, Thomas E ^a   Ullman, Buddy ^b  

^a Department of Pharmaceutical Chemistry ^*  (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 BROMO CYCLIC AMP; BUCLADESINE; CYCLIC AMP DEPENDENT PROTEIN KINASE; HEXANOIC ACID; ISOBUTYRIC ACID; LAURIC ACID; MERCAPTOPURINE; MERCAPTOPURINE RIBOSIDE; PALMITIC ACID; PHOSPHODIESTERASE; PRODRUG; THEOPHYLLINE;

2' O ACYL 6 THIOINOSINE 3',5' PHOSPHATE; 2' O BUTYRYLADENOSINE 3',5' PHOSPHATE; 6 THIOINOSINE 3',5' PHOSPHATE; 6 THIOINOSINE 3',5' PHOSPHATE DERIVATIVE; CYTOTOXICITY; DOSE RESPONSE; DRUG ANALYSIS; DRUG COMPARISON; DRUG RESISTANCE; DRUG RESPONSE; DRUG SCREENING; DRUG STABILITY; DRUG SYNTHESIS; GENETICS; HEREDITY; IN VITRO STUDY; LIPOPHILICITY; LYMPHOMA; MUTATION; PHARMACOKINETICS; S49 CELL; STRUCTURE ACTIVITY RELATION; THEORETICAL STUDY; THIOINOSINATE;

ANIMAL; ANTINEOPLASTIC AGENTS; CYCLIC AMP; DRUG RESISTANCE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; INOSINE; LYMPHOMA; MICE; NEOPLASMS, EXPERIMENTAL; NUCLEOTIDES, CYCLIC; SUPPORT, U.S. GOV'T, P.H.S.; THIOINOSINE; THIONUCLEOTIDES; TIME FACTORS;

EID: 0018682367     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00193a012     Document Type: Article

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