Enhancement of Endotoxic Shock by W-Acetylmuramyl-L-alanyl-(L-seryl)-D-isoglutamine (Muramyl Dipeptide)

Cancer Research

Volumn 39, Issue 11, 1979, Pages 4756-4759

  Ribi, Edgar E ^a   Cantrell, John L ^a   Von Eschen, Kenneth B ^a   Schwartzman, Steven M ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTOXIN; MURAMYL DIPEPTIDE;

ANIMAL EXPERIMENT; CANCER; CARDIOVASCULAR SYSTEM; GUINEA PIG; IMMUNOTHERAPY; SEPTIC SHOCK; SKIN CANCER; TREHALOSE MYCOLATE; TUMOR;

ACETYLMURAMYL-ALANYL-ISOGLUTAMINE; ANIMAL; CORD FACTORS; ENDOTOXINS; GLYCOPEPTIDES; GUINEA PIGS; IMMUNOTHERAPY; MYCOBACTERIUM BOVIS; NEOPLASMS; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHIMURIUM; SHOCK, SEPTIC;

EID: 0018569936     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Azuma, I., Ribi, E. E., Meyer, T. J. and Zbar, B. Biologically active components from mycobacterial cell walls. I. Isolation and composition of cell wall skeleton and component P3. J. Natl. Cancer Inst., 52: 95–101, 1974.
2. Chen, C. H., Johnson, A. G., Kasai, N., Key, B. A., Levin, J., and Nowotny, A. Heterogeneity and biological activity of endotoxic glycolipid from Salmonella minnesota R595. J. Infect. Dis., 128: S43-S51, 1973.
3. Hortobagyi, G. N., Gutterman, J. U., Snyder, R. D., Richman, S. P., and Hersh, E. M. Pseudomonas vaccine: A phase I evaluation for cancer research. Cancer Immunol. Immunother., 4: 201–207, 1978.
4. Lederer, E. Natural and synthetic immunostimulants related to the ipycobacterial cell wall. In: Medicinal Chemistry V. Proceedings of the Fifth International Symposium on Medicinal Chemistry, pp. 257–279. Amsterdam: Elsevier Scientific Publishing Co., 1977.
5. Lefrancier, P., Choay, J., Derrien, M. and Lederman, I. Synthesis of N-acetyl-muramyl-L-alanyl-o-isoglutamine, an adjuvant of the immune response, and of some N-acetyl-muramyl-peptide analogs. Int. J. Pept. Protein Res., 9. 249–257, 1977.
6. Meyer, T. J., Ribi, E., Azuma, I., and Zbar, B. Biologically active components from mycobacterial cell walls. II. Suppression and regression of strain-2 guinea pig hepatoma. J. Natl. Cancer Inst., 52; 103–111, 1974.
7. Milner, K. C., and Finkelstein, R. A. Bioassay of endotoxin: Correlation between pyrogenicity for rabbits and lethality for chick embryos. J. Infect. Dis., 116:529–536, 1966.
8. Rapp, H. J. A guinea pig model for tumor immunology. A summary. Isr. J. Med. Sci., 9. 366–374, 1973.
9. Ribi, E., Anacker, R. L., Brehmer, W., Goode, G., Larson, C. L., List, R. H., Milner, K. C., and Wicht, W. C. Factors influencing protection against experimental tuberculosis in mice by heat-stable cell wall vaccines. J. Bacterioi. 92. 869–879, 1966.
10. Ribi, E., Granger, D. L., Milner, K. C., and Strain, S. M. Brief communication. Tumor regression caused by endotoxin and mycobacterial fractions. J. Natl. Cancer Inst., 55. 1253–1257, 1975.
11. Ribi, E., Parker, R. and Milner, K. C. Microparticulate gel chromatography accelerated by centrifugal force and pressure. In: D. Glick (ed.), Methods of Biochemical Analysis. Vol. 22, pp. 355–400. New York: John Wiley & Sons, Inc., 1974.
12. Ribi, E., Takayama, K., Milner, K. C., Gray, G. R. Goren, M. B., Parker, R., McLaughlin, C. A., and Kelly, M. Regression of tumors by an endotoxin combined with trehalose mycolates of differing structure. Cancer Immunol. Immunother., 1: 265–270, 1976.
13. Suter, E., and Kirsanow, E. M. Hyperreactivity to endotoxin in mice infected with mycobacteria. Induction and elicitation of the reactions. Immunology, 4: 354-365,1961.
14. Westphal, O., Lüderitz, O. and Bister, F. über die Extraktion von Bakterien mit Phenol/Wasser. Z. Naturforsch., Sect. C Biosci, 7. 148–155, 1952.
15. Yarkoni, E., Meltzer, M. S., and Rapp, H. J. Failure of trehalose 6,6'-dimycolate (P3 or cord factor) to enhance endotoxin lethality in mice. Infect. Immun., 14:1375–1377, 1976.