The Penems, a New Class of β-Lactam Antibiotics: 6-Acylaminopenem-3-carboxylic Acids1

Journal of the American Chemical Society

Volumn 100, Issue 26, 1978, Pages 8214-8222

  Ernest, I ^a   Gosteli, J ^a   Greengrass, C W ^a   Holick, W ^a   Jackman, D E ^a   Pfaendler, H R ^a   Woodward, R B ^a  

^a (The Former) Woodward Research Institute   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

6 AMINOPENEM 3 CARBOXYLIC ACID DERIVATIVE; DRUG ANALYSIS; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; INFRARED SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; STAPHYLOCOCCUS AUREUS; THEORETICAL STUDY; ULTRAVIOLET SPECTROPHOTOMETRY;

EID: 0018233237     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja00494a032     Document Type: Article

References (16)

1. Some of the investigations described in this paper were presented by R.B.W. In lectures, given before the Swedish Chemical Society In Stockholm on Dec. 9, 1975, and before The Chemical Society at Cambridge on June 29, 1976. Cf. R. B. Woodward, “Recent Advances In the Chemistry of /J-Lactam Antibiotics”, Chem. Soc., Spec. Publ., No, 28, 167 (1977).
2. R. B. Woodward in “The Chemistry of Penicillin”, H. T, Clarke, J. R. Johnson, and R. Robinson, Ed., Princeton University Press, Princeton, N.J., 1949, p 440.
3. a). D. Crowfoot, C. W. Bunn, D. W. Rogers-Low, and A. Turner-Jones in ref 2, p 310
4. R. M. Sweet in “Cephalosporins and Penicillins: Chemistry and Biology”, E. H. Flynn, Ed., Academic Press, New York, N.Y., 1972, p 280.
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