Influence of Inclusion of Nonsteroidal Antiinflammatory Drugs with b-Cyclodextrin on the Irritation to Stomach of Rats upon Oral Administration

Chemical and Pharmaceutical Bulletin

Volumn 26, Issue 12, 1978, Pages 3609-3612

  Nambu, Naoki ^a   Takahashi, Yasuyuki ^b   Ueda, Haruhisa ^c   Nagai, Tsuneji ^c   Kikuchi, Kyoko ^c   Kikuchi, Takaaki ^c  

^a Hoshi Institute of Pharmaceutical Sciences ^*  (Japan)

^b Laboratory of Wakamoto Pharmaceutical Company ^*  (Japan)

^c Wakamoto Pharmaceutical Co   (Japan)

Author keywords

inclusion compound cyclodextrin; indomethacin flufenamic acid phenylbutazone; injury of stomach Wistar male rat

Indexed keywords

BETA CYCLODEXTRIN; FLUFENAMIC ACID; INDOMETACIN; PHENYLBUTAZONE;

ADVERSE DRUG REACTION; ANIMAL EXPERIMENT; DRUG COMPARISON; DRUG FORMULATION; DRUG TOLERANCE; ORAL DRUG ADMINISTRATION; RAT; STOMACH; STOMACH IRRITATION;

ADMINISTRATION, ORAL; ANIMALS; ANTI-INFLAMMATORY AGENTS; DEXTRINS; MALE; RATS; STARCH; STOMACH;

EID: 0018222817     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.26.3609     Document Type: Article

References (4)

1. T. Nagai and N. Nambu, FIP Abstracts (Dublin, 1975), p. 55.
2. M. Kurozumi, N. Nambu, and T. Nagai, Chem. Pharm. Bull. (Tokyo), 23, 3062 (1975).
3. N. Nambu, M. Shimoda, Y. Takahashi, H. Ueda, and T. Nagai, Chem. Pharm. Bull. (Tokyo), 26, 2952 (1978).
4. N. Nambu, M. Shimoda, Y. Takahashi, M. Tsai, H. Ueda, and T. Nagai