Effect of Structure on Tumor Specificity of Alicyclic α-Amino Acids

Cancer Research

Volumn 38, Issue 8, 1978, Pages 2271-2273

  Washburn, Lee C ^a   Sun, Tan Tan ^a   Anon, Jack B ^a   Hayes, Raymond L ^a  

^a OAK RIDGE ASSOCIATED UNIVERSITIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CYCLOBUTANE DERIVATIVE; CYCLOHEXANECARBOXYLIC ACID DERIVATIVE; CYCLOLEUCINE; CYCLOPROPANE DERIVATIVE; DRUG DERIVATIVE; RADIOISOTOPE;

ANIMAL; ARTICLE; COMPARATIVE STUDY; EXPERIMENTAL NEOPLASM; LIVER CELL CARCINOMA; LIVER TUMOR; MALE; METABOLISM; NEOPLASM; RAT; SCINTISCANNING; STRUCTURE ACTIVITY RELATION; TISSUE DISTRIBUTION; TOMOGRAPHY; ALICYCLIC AMINO ACID; AMINO ACID C 11; ANIMAL EXPERIMENT; CANCER GRAFT; CANCER LOCALIZATION; CYCLOLEUCINE C 14; KIDNEY; MALE GENITAL SYSTEM; MORRIS HEPATOMA; MUSCLE; PHARMACOKINETICS; SCINTIGRAPHY; TESTIS;

AMINO ACIDS; ANIMAL; CARCINOMA, HEPATOCELLULAR; COMPARATIVE STUDY; CYCLOBUTANES; CYCLOHEXANECARBOXYLIC ACIDS; CYCLOLEUCINE; CYCLOPROPANES; LIVER NEOPLASMS; MALE; NEOPLASMS; NEOPLASMS, EXPERIMENTAL; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, U.S. GOV'T, P.H.S.; TISSUE DISTRIBUTION; TOMOGRAPHY, X-RAY COMPUTED;

EID: 0018199478     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Berlinguet, L., Bégin, N., and Babineau, L. M. Autoradiographic Studies of the Distribution of 1-Aminocyclopentane Carboxylic Acid in Normal and Cancerous Mice. Can. J. Biochem., 40: 1111-1114, 1962.
2. Christensen, H. N. Mode of Transport of Amino Acids into Cells. In: W. D. McElroy and H. B. Glass (eds.), A Symposium on Amino Acid Metabolism, pp. 63–106. Baltimore: The Johns Hopkins Press, 1955.
3. Christensen, H. N. Biological Transport, Ed. 2, p. 187. Reading, Mass.: W. A. Benjamin, Inc., 1975.
4. Connors, T. A., and Ross, W. C. J. Some Derivatives of 1-Aminocyclopentanecarboxylic Acid and Related Compounds. J. Chem. Soc., 2119-2132, 1960.
5. Dox, A. W., and Yoder, L. Spiro-Pyrimidines. III. Condensation of Cyclopropane-1,1-dicarboxylic Ester with Ureas. J. Am. Chem. Soc., 43: 2097-2101, 1921.
6. Hayes, R. L., Washburn, L. C., Wieland, B. W., Sun, T. T., Anon, J. B., Butler, T. A., and Callahan, A. P. Synthesis and Purification of 11C-Carboxyl-Labeled Amino Acids. Intern. J. Appl. Radiation Isotopes, in press, 1978.
7. Hayes, R. L., Washburn, L. C., Wieland, B. W., Sun, T. T., Turtle, R. R., and Butler, T. A. Carboxyl-Labeled 11C-1-Aminocyclopentanecarboxylic Acid, a Potential Agent for Cancer Detection. J. Nucl. Med., 17: 748-751, 1976.
8. Holley, R. W. A Unifying Hypothesis Concerning the Nature of Malignant Growth. Proc. Natl. Acad. Sci. U. S., 69: 2840-2841, 1972.
9. Hübner, K. F., Andrews, G. A., Washburn, L., Wieland, B. W., Gibbs, W. D., Hayes, R. L., Butler, T. A., and Winebrenner, J. D. Tumor Location with 1-Aminocyclopentane[11C] Carboxylic Acid: Preliminary Clinical Trials with Single-Photon Detection. J. Nucl. Med., 18: 1215-1221, 1977.
10. Phelps, M. E. Emission Computed Tomography. Seminars Nucl. Med., 7: 337-365, 1977.
11. Phelps, M. E., Hoffman, E. J., Mullani, N. A., and Ter-Pogossian, M. M. Application of Annihilation Coincidence Detection to Transaxial Reconstruction Tomography. J. Nucl. Med., 16: 210-224, 1975.
12. Washburn, L. C., Sun, T. T., Wieland, B. W., and Hayes, R. L. C-11-dl-Tryptophan, a Potential Pancreas-Imaging Agent for Positron Tomography (Abstract). J. Nucl. Med., 18: 638, 1977.
13. Washburn, L. C., Wieland, B. W., Sun, T. T., Hayes, R. L., and Butler, T. A. [1-11C] DL-Valine, a Potential Pancreas-Imaging Agent. J. Nucl. Med., 19: 77-83, 1978.