Oxygen-Dependent Microbial Killing by Phagocytes

New England Journal of Medicine

Volumn 298, Issue 13, 1978, Pages 721-725

  Babior, Bernard M ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OXYGEN;

BACTERIUM; BLOOD AND HEMOPOIETIC SYSTEM; CELL KILLING; EDITORIAL; PHAGOCYTE; PHAGOCYTOSIS;

BACTERIA; BACTERIAL INFECTIONS; CHILD, PRESCHOOL; FEMALE; GLUCOSEPHOSPHATE DEHYDROGENASE DEFICIENCY; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GRANULOMATOUS DISEASE, CHRONIC; HUMAN; MALE; OXYGEN CONSUMPTION; PEROXIDASE; PHAGOCYTES; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0018178223     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM197803302981305     Document Type: Review

References (34)

1. Berendes H, Bridges RA, Good RA: A fatal granulomatosis of childhood: the clinical study of a new syndrome. Minn Med 40: 309–312, 1957
2. Johnston RB Jr, Baehner RL: Chronic granulomatous disease: correlation between pathogenesis and clinical findings. Pediatrics 48: 730–739, 1971
3. Dilworth JA, Mandell GL: Adults with chronic granulomatous disease of “childhood.” Am J Med 63: 233–243, 1977
4. Windhorst DB, Page AR, Holmes B, et al: The pattern of genetic transmission of the leukocyte defect in fatal granulomatous disease of childhood. J Clin Invest 47: 1026–1034, 1968
5. Azimi PH, Bodenbender JH, Hintz RL, et al: Chronic granulomatous disease in three female siblings. JAMA 206: 2865–2870, 1968
6. DeChatelet LR, Shirley PS, McPhail LC: Normal leukocyte glutathione peroxidase activity in patients with chronic granulomatous disease. J Pediatr 89: 598–600, 1976
7. Baehner RL, Nathan DG: Leukocyte oxidase: defective activity in chronic granulomatous disease. Science 155: 835–836, 1967
8. Mandell GL, Hook EW: Leukocyte function in chronic granulomatous disease of childhood: studies on a seventeen year old boy. Am J Med 47: 473–486, 1969
9. Curnutte JT, Whitten DM, Babior BM: Defective Superoxide production by granulocytes from patients with chronic granulomatous disease. N Engl J Med 290: 593–597, 1974
10. Stossel TP, Root RK, Vaughan M: Phagocytosis in chronic granulomatous disease and the Chediak-Higashi syndrome. N Engl J Med 286: 120–123, 1972
11. Quie PG, White JG, Holmes B, et al: In vitro bactericidal capacity of human polymorphonuclear leukocytes: diminished activity in chronic granulomatous disease of childhood. J Clin Invest 46: 668–679, 1967
12. Baehner RL, Karnovsky MT, Karnovsky ML: Degranulation of leukocytes in chronic granulomatous disease. J Clin Invest 48: 187–192, 1969
13. Gold SB, Hanes DM, Stites DP, et al: Abnormal kinetics of degranulation in chronic granulomatous disease. N Engl J Med 291: 332–337, 1974
14. Klebanoff SJ, White LR: Iodination defect in the leukocytes of a patient with chronic granulomatous disease of childhood. N Engl J Med 280: 460–466, 1969
15. Mandell GL, Hook EW: Leukocyte bactericidal activity in chronic granulomatous disease: correlation of bacterial hydrogen peroxide production and susceptibility to intracellular killing. J Bacteriol 100: 531–532, 1969
16. Johnston RB Jr, Baehner RL: Improvement of leukocyte bactericidal activity in chronic granulomatous disease. Blood 35: 350–355, 1970
17. Westminster Hospitals Bone-Marrow Transplant Team: Bone marrow transplant from an unrelated donor for chronic granulomatous disease. Lancet 1: 210–213, 1977
18. Philippart AI, Colodny AH, Baehner RL: Continuous antibiotic therapy in chronic granulomatous disease: preliminary communication. Pediatrics 50: 923–925, 1972
19. Johnston RB Jr, Wilfert CM, Buckley RH, et al: Enhanced bactericidal activity of phagocytes from patients with chronic granulomatous disease in the presence of sulphisoxazole. Lancet 1: 824–827, 1975
20. Baehner RL, Johnston RB Jr, Nathan DG: Comparative study of the metabolic and bactericidal characteristics of severely glucose-6-phosphate dehydrogenase deficient polymorphonuclear leukocytes and leukocytes from children with chronic granulomatous disease. J Reticuloendothel Soc 12: 150–169, 1972
21. Gray GR, Klebanoff SJ, Stamatoyannopoulos G, et al: Neutrophil dysfunction, chronic granulomatous disease, and nonspherocytic haemolytic anaemia caused by complete deficiency of gIucose-6-phosphate dehydrogenase. Lancet 2: 530–534, 1973
22. Patriarca P, Cramer R, Tedesco F, et al: Studies on the mechanism of metabolic stimulation in polymorphonuclear leucocytes during phagocytosis. II. Presence of the NADPH2 oxidizing activity in a myeloperoxidase-deficient subject. Biochim Biophys Acta 385: 387–393, 1975
23. Stendahl O, Lindgren S: Function of granulocytes with deficient myeloperoxidase-mediated iodination in a patient with generalized pustular psoriasis. Scand J Haematol 16: 144–153, 1976
24. Klebanoff SJ, Clark RA: Iodination by human polymorphonuclear leukocytes: a re-evaluation. J Lab Clin Med 89: 675–686, 1977
25. Rosen HS, Klebanoff SJ: Chemiluminescence and Superoxide production by myeloperoxidase-deficient leukocytes. J Clin Invest 58: 50–60, 1976
26. Klebanoff SJ, Pincus SH: Hydrogen peroxide utilization in myeloper-oxidase-deficient leukocytes: a possible microbicidal control mechanism. J Clin Invest 50: 2226–2229, 1971
27. Jandl RC, Andre-Schwartz J, Borges-Dubois L, et al: Termination of the respiratory burst in human neutrophils. J Clin Invest (in press)
28. Klebanoff SJ: Myeloperoxidase: contribution to the microbicidal activity of intact leukocytes. Science 169: 1095–1097, 1970
29. Loos H, Roos D, Weening R, et al: Familial deficiency of glutathione reductase in human blood cells. Blood 48: 53–62, 1976
30. Weening RS, Roos D, van Schaik MLJ, et al: The role of glutathione in the oxidative metabolism of phagocytic leukocytes: studies in a family with glutathione reductase deficiency, Movement, Metabolism and Bacterial Mechanisms of Phagocytes. Edited by F Rossi, P Patriarca, D Romeo. Padua, Piccin Editore, 1977, pp 277–285
31. Quie PG, Kaplan EL,Page AR, et al: Defective polymorphonuclear leukocyte function and chronic granulomatous disease in two female children. N Engl J Med 278: 976–980, 1968
32. Holmes B, Park BH, Malawista SE, et al: Chronic granulomatous disease in females: a deficiency of leukocyte glutathione peroxidase. N Engl J Med 283: 217–221, 1970
33. Matsuda I, Oka Y, Taniguchi N, et al: Leukocyte glutathione peroxidase deficiency in a male patient with chronic granulomatous disease. J Pediatr 88: 581–583, 1976
34. Baehner RL, Gilman N, Karnovsky ML: Respiration and glucose oxidation in human and guinea pig leukocytes: comparative studies. J Clin Invest 49: 692–700, 1970