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Volumn 3, Issue 12, 1978, Pages

Enkephalin-like immunoreactivity in gland cells and nerve terminals of the adrenal medulla

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ENDORPHIN; BETA ENDORPHIN; LEUCINE ENKEPHALIN; METENKEPHALIN;

EID: 0018126149     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-4522(78)90137-9     Document Type: Article
Times cited : (444)

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    • The following recent findings are pertinent to our observations and discussion. Enkephalin-like immunoreactivity has recently been described in adrenal medullary tumours on the basis of radioimmunoassay (Sullivan,Bloom &Polak, 1978).In relation to the nature of the immunoreactive reactive material, it is noteworthy that an enkephalin-like immunoreactive substance resistant to enzymatic break-down has recently been found in the cerebrospinal fluid (Sarne,Azov &Weissman, 1978).Concerning the question whether enkephalin-like material, if secreted from the adrenal gland, can have any endocrine function, it is relevant that intra-arterially infused met-enkephalin can in fact exert peripheral effects (Konturek,Pawlik,Walus,Coy &Schally, 1978) and that enkephalin-like peptide(s) resistant to enzymatic break-down seem to exist (Srane et al, 1978).


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