Heterogeneity of Tumor Cells from a Single Mouse Mammary Tumor

Cancer Research

Volumn 38, Issue 10, 1978, Pages 3174-3181

  Dexter, Daniel L ^a   Kowalski, Henryk M ^b   Blazar, Beverly A ^b   Fligiel, Zuzana ^b   Vogel, Renee ^b   Gloria, H ^b   Heppner, H ^b  

^a BROWN UNIVERSITY   (United States)

^b ROGER WILLIAMS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS ANTIGEN;

ANIMAL EXPERIMENT; BREAST; BREAST CARCINOMA; CANCER CELL CULTURE; CANCER GRAFT; CANCER GROWTH; ELECTRON MICROSCOPY; HEREDITY; HISTOLOGY; IN VITRO STUDY; KARYOTYPE; MOUSE; MOUSE MAMMARY TUMOR ONCOVIRUS;

ADENOCARCINOMA; ANIMALS; ANTIGENS, SURFACE; ANTIGENS, VIRAL; CELL DIVISION; CELL LINE; CHROMOSOME ABERRATIONS; CLONE CELLS; FEMALE; KINETICS; MAMMARY NEOPLASMS, EXPERIMENTAL; MAMMARY TUMOR VIRUS, MOUSE; MICE; MICE, INBRED BALB C; MICE, INBRED C3H;

EID: 0018083233     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Barranco, S. C., Drewinko. B., Ho, D., Humphrey, R. M., and Romsdahl, M. M. Differential Sensitivities of Human Melanoma Cells Grown in Vitro to Arabinosylcytosine. Cancer Res., 32: 2733-2736, 1972.
2. Barranco, S. C., Drewinko, B., and Humphrey, R. M. Differential Response by Human Melanoma Cells to 1,3,-(bis)-(2-chloramethyl)-1-nitrosourea and Bleomycin. Mutation Res., 19: 277-280, 1973.
3. Becker, F. F., Klein, K. M., Wolman, S. R., Asofsky, R., and Sell, S. Characterization of Primary Hepatocellular Carcinomas and Initial Transplant Generations. Cancer Res., 33: 3330-3338, 1973.
4. Boon, T., Buckingham, M. E., Dexter, D. L., Jacob, H., and Jacob, F. Teratocarcinome de la Souris: Isolement et Proprietes de Deux Lignes de Myoblasts. Ann. Microbiol. Inst. Pasteur, 125B: 13-28, 1974.
5. Butel, J. S., Dudley, J. P., and Medina, D. Comparison of the Growth Properties in Vitro and Transplantability of Continuous Mouse Mammary Tumor Cell Lines and Clonal Derivatives. Cancer Res., 37: 1892-1900, 1977.
6. Dunn, T., Morphology of Mammary Tumors in Mice. In: F. Homburger and N. H. Fishman (eds.), Physiopathology of Cancer, Ed. 2, pp. 38-84. New York: Paul B. Hoeber, Inc., 1959.
7. Fidler, I. J., and Kripke, M. L. Metastasis Results from Preexisting Variant Cells within a Malignant Tumor. Science, 197: 893-895, 1977.
8. Fine, D. L., Arthur, L. O., Plowman, J. K., Hillman, E. A., and Klein, F. In Vitro System for Production of Mouse Mammary Tumor Virus. Appl. Microbiol., 28: 1040-1048, 1975.
9. Gray, J. M., and Pierce, G. B. Relationship between Growth Rate and Differentiation of Melanoma in Vivo. J. Natl. Cancer Inst., 32: 1201-1211, 1964.
10. Hager, J. C., and Tompkins, W. A. F. Antibodies in Normal Rabbit Serum That React with Tissue Specific Antigens on the Plasma Membranes of Human Adenocarcinoma Cells. J. Natl. Cancer Inst., 56: 339-344, 1976.
11. Hakannson, L., and Trope, C. On the Presence within Tumors of Clones that Differ in Sensitivity to Cytostatic Drugs. Acta Pathol. Microbiol. Scand. A, 82: 35-40, 1974.
12. Hauschka, T. S., and Levan, A. Cytologic and Functional Characterization of Single Cell Clones Isolated from the Krebs-2 and Ehrlich Ascites Tumors. J. Natl. Cancer Inst., 21: 77-135, 1958.
13. Henderson, J. S., and Rous, P. The Plating of Tumor Components on the Subcutaneous Expanses of Young Mice. J. Exptl. Med., 115: 1211-1229,1962.
14. Klein. G., and Klein, E. Conversion of Solid Neoplasms into Ascites Tumors. Ann. N. Y. Acad. Sci., 63: 640-661, 1956.
15. Mitelman, F., Mark, J., Levan, G., and Levan, A. Tumor Etiology and Chromosome Pattern. Science, 176: 1340-1341, 1972.
16. Nowell, P. C. The Clonal Evolution of Tumor Cell Populations. Science, 194: 23-28, 1976.
17. Pimm, M. V., and Baldwin, R. W. Antigenic Differences between Primary Methylcholanthrene-lnduced Rat Sarcomas and Post-Surgical Recurrences. Intern. J. Cancer, 20: 37-43, 1977.
18. Prehn, R. T. Analysis of Antigenic Heterogeneity within Individual 3-Methylcholanthrene Induced Mouse Sarcomas. J. Natl. Cancer. Inst., 45:1039-1045,1970.
19. Pretlow, T., and Boone, C. Separation of Mammalian Cells using Programmed Gradient Sedimentation. Exptl. Mol. Pathol., 11: 139-152, 1969.
20. Schabel, F. M., Jr. Concepts for Systemic Treatment of Micrometastases. Cancer, 35:15-24,1975.
21. Sluyser, M. and Van Nie, R. Estrogen Receptor Content and Hormone-responsive Growth of Mouse Mammary Tumors. Cancer Res., 34: 3253-3257,1974.
22. Takahashi, M. Color Atlas of Cancer Cytology, pp. 46-56. Philadelphia: J. B. Lippincott Co., 1971.
23. Zettergren, J., Luberoff, P., and Pretlow, T. Separation of Lymphocytes from Disaggregated Mouse Malignant Neoplasms by Sedimentation in Gradients of Ficoll in Tissue Culture Medium. J. Immunol., 111: 833-840,1973.