Disposition of sodium valproate in epileptic patients.

British Journal of Clinical Pharmacology

Volumn 5, Issue 6, 1978, Pages 495-499

  Perucca, E ^a   Gatti, G ^a   Frigo, GM ^a   Crema, A ^a   Calzetti, S ^a   Visintini, D ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; VALPROIC ACID;

DRUG BLOOD LEVEL; DRUG INTERACTION; EPILEPSY; INTRAVENOUS DRUG ADMINISTRATION; ORAL DRUG ADMINISTRATION;

ADULT; ANTICONVULSANTS; EPILEPSY; HALF-LIFE; HUMANS; KINETICS; MALE; VALERATES; VALPROIC ACID;

EID: 0017850444     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.1978.tb01663.x     Document Type: Article

References (14)

1. Oral disposition of valproic acid following single and multiple doses. Naun. Schmd
2. Changes in drug metabolism with increasing age. Phenytoin clearance and protein binding
3. Preliminary observations on the protein binding and enzyme‐inducing properties of sodium valproate (Epilim)
4. Pharmacokinetics and bioavailability of sodium valproate
5. Valproate may lower serum Phenytoin
6. Clearance and biological half‐lives as indices of intrinsic hepatic metabolism
7. Pharmacokinetics of sodium valproate after oral and intravenous administration
8. Pharmacokinetics and efficacy of Epilim in patients receiving long‐term therapy with other antiepileptic drugs
9. Pharmacokinetics of di‐N‐propylacetate in epileptic patients
10. Determination of the anti‐convulsant drug sodium di‐n‐propylacetate in human plasma by gas chromatography
11. A physiological approach to hepatic drug clearance