Induction of dominant-lethal mutations after administration of ethylenethiourea in combination with nitrite or of N-nitroso-ethylenethiourea in mice

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 56, Issue 3, 1978, Pages 335-340

  Teramoto, S ^a   Shingu, A ^a   Shirasu, Y ^a  

^a INSTITUTE OF ENVIRONMENTAL TOXICOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

NITRITE; SODIUM NITRITE;

2 IMIDAZOLINETHIONE; ANIMAL EXPERIMENT; DOMINANT LETHAL MUTANT; DOMINANT LETHAL TEST; DRUG MIXTURE; LETHAL GENE; MOUSE; MUTANT; N NITROSOIMIDAZOLIDINE 2 THIONE; ORAL DRUG ADMINISTRATION; PREGNANCY;

ANIMAL; DRUG THERAPY, COMBINATION; ETHYLENETHIOUREA; GENES, DOMINANT; GENES, LETHAL; IMIDAZOLES; MALE; MICE; MICE, INBRED C3H; MUTAGENS; NITRITES; NITROSO COMPOUNDS;

EID: 0017838639     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/0027-5107(78)90202-6     Document Type: Article

References (14)

1. Determination of the degradation products of ethylene-bis-(dithiocarbamates) by thin-layer chromatography and some investigations of their decomposition in vitro
2. Comparison of radiation- and chemically-induced dominant lethal mutations in male mice
3. Bioassay of pesticides and industrial chemicals for tumorigenicity in mice: a preliminary note
4. Ethylenethiourea: teratogenicity study in rats and rabbits
5. Formation of N-nitroso compounds: chemistry, kinetics, and in vivo occurrence
6. Mutagenic and carcinogenic N-nitroso compounds: possible environmental hazards
7. Mutagenicity of nitrosamides and nitrosamidines in micro-organisms and plants
8. The activity of some nitroso compounds in the mouse dominant-lethal mutation assay
9. Ethylenethiourea (ETU), a carcinogenic and mutagenic metabolite of ethylenebis-dithiocarbamate
10. In vivo mutagenic interaction of nitrite and ethylenethiourea
11. Nitrosation in vitro and in vivo by sodium nitrite, and mutagenicity of nitrogenous pesticides
12. Mutagenicity screening on pesticides and modification products: a basis of carcinogenicity evaluation
13. Mutagenicity testing on ethylenethiourea
14. Thyroid cancer in rats from ethylene thiourea intake