The monoclonality of human B-cell lymphomas*

Journal of Experimental Medicine

Volumn 145, Issue 4, 1977, Pages 1014-1028

  Levy, Ronald ^a,b   Warnke, Roger ^a,b   Dorfman, Ronald F ^a,b   Haimovich, Joseph ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

LYMPHOCYTE MEMBRANE IMMUNOGLOBULIN;

B LYMPHOCYTE; DIAGNOSIS; ETIOLOGY; HISTOLOGY; IMMUNOFLUORESCENCE; IN VITRO STUDY; LYMPHOMA; MAJOR CLINICAL STUDY;

B-LYMPHOCYTES; CELL LINE; FLUORESCENT ANTIBODY TECHNIQUE; HUMAN; IMMUNOGLOBULINS, KAPPA-CHAIN; IMMUNOGLOBULINS, LAMBDA-CHAIN; IMMUNOGLOBULINS, SURFACE; LYMPHOMA;

EID: 0017694533     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.145.4.1014     Document Type: Article

References (54)

1. Friedman, J. M., and P. J. Fialkow. 1976. Cell marker studies of human tumorigenesis. Transplant. Rev. 28:2.
2. Fialkow, P. J., R. W. Sogebid, S. M. Gartler, and D. L. Rimoin. 1971. Multiple cell origin of hereditary neurofibromas. N. Engl. J. Med. 284:298.
3. Gartler, S. M., L. Ziprkowski, A. Krakowski, R. Egra, A. Szeinberg, and A. Adam. 1966. Glucose-6-phosphate dehydrogenase mosaicism as a tracer in the study of hereditary multiple trichoepithelioma. Am. J. Hum. Genet. 18:282.
4. Linder, D., B. K. McCaw, and F. Hecht. 1975. Parthenogenic origin of benign ovarian teratomas. N. Engl. J. Med. 292:63.
5. Moore, M. A. S., H. Ekert, M. G. Fitzgerald, and A. Carmichael. 1974. Evidence for the clonal origin of chronic myeloid leukemia from a sex chromosome mosaic: clinical, cytogenic, and marrow culture studies. Blood. 43:15.
6. Lyon, M. F. 1972. X-chromosome inactivation and developmental patterns in mammals. Biol. Rev. 47:1.
7. Martenson, L. 1963. On a key point of modem biochemical genetics. Lancet. 1:946.
8. Preud’homme, J. L., and M. Seligmann. 1972. Surface bound immunoglobulin as a cell marker in human lymphoproliferative diseases. Blood. 40:777.
9. Aisenberg, A. C., and K. J. Bloch. 1975. Immunoglobulins on the surface of neoplastic lymphocytes. N. Engl. J. Med. 187:272.
10. Gajl-Peczalska, J. K., C. D. Bloomfield, P. F. Coccia, H. Sosin, R. D. Brunning, and J. H. Kersey. 1975. B and T cell lymphomas. Analysis of blood and lymph nodes in 87 patients. Am. J. Med. 59:674.
11. Leech, J. H., A. D. Glick, J. A. Waldron, J. M. Flexner, R. G. Horn, and R. D. Collins. 1975. Malignant lymphomas of follicular center cell origin in man. I. Immunologic studies. J. Natl. Cancer Inst. 54:11.
12. Mann, R. B., E. S. Jaffe, R. C. Braylan, K. Nanba, M. Frank, J. L. Ziegler, and C. W. Berard. 1976. Non-endemic Burkitt’s lymphoma: a B-cell tumor related to germinal centers. N. Engl. J. Med. 295:685.
13. Nisonoff, A., J. E. Hopper, and S. B. Spring. 1975. The Antibody Molecule. Academic Press, Inc., New York. 542.
14. Gearhart, P. J., N. H. Sigal, and N. R. Klinman. 1975. Production of antibodies of identical idiotype but diverse immunoglobulin classes by cells derived from a single stimulated B cell. Proc. Natl. Acad. Sci. U.S.A. 72:1707.
15. Wang, A. C., S. K. Wilson, J. E. Hopper, H. H. Feidenberg, and A. Nisonoff. 1970. Evidence for control of synthesis of the variable regions of the heavy chains of immunoglobulins G and M by the same gene. Proc. Natl. Acad. Sci. U.S.A. 66:337.
16. Pemis, B., L. Fomi, and L. Amante. 1971. Immunoglobulins as cell receptors. Ann. N. Y. Acad. Sci. 190:420.
17. Rowe, D. S., K. Hug, L. Forni, and B. Pernis. 1973. Immunoglobulin D as a lymphocyte receptor. J. Exp. Med. 138:965.
18. Fu, S. M., R. J. Winchester, and H. G. Kunkel. 1974. Occurrence of surface IgM, IgD, and free light chains of human lymphocytes. J. Exp. Med. 139:451.
19. Fu, S. M., R. J. Winchester, and H. G. Kunkel. 1975. Similar idiotype specificity for the membrane IgD and IgM of human B lymphocytes. J. Immunol. 114:250.
20. Brouet, J. C., J. L. Preud’homme, G. Flandrin, N. Chelloul, and M. Seligmann. 1976. Membrane markers in "histiocytic" lymphomas (reticulum cell sarcomas). J. Natl. Cancer Inst. 56:631.
21. Axen, R., J. Porath, and S. Ernback. 1967. Chemical coupling of peptides and proteins to polysaccharides by means of cyanogen halides. Nature (Lond.). 241:1302.
22. Laemmli, U.K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond.). 227:680.
23. Levy, H. B., and H. A. Sober. 1960. A simple chromatographic method for preparation of gamma globulin. Proc. Soc. Exp. Biol. Med. 103:250.
24. Nisonoff, A., F. C. Wissler, L. H. Lipman, and D. L. Woernely. 1960. Separation of univalent fragments from the bivalent rabbit antibody by reduction of diffusable bonds. Arch. Biochem. Biophys. 89:230.
25. Ouchterlony, O. 1958. Diffusion-in-gel methods for immunological analysis. Prog. Allergy. 5:1.
26. Hunter, W. M. 1973. In Handbook of Experimental Immunology. D. M. Wein, editor. Blackwell Scientific Publications, Ltd., Oxford, Great Britain. 17.1-17.37.
27. 131I-labeled human growth hormone of high specific radioactivity. Biochem. J. 89:114.
28. Cebra, J. J., and G. Goldstein. 1965. Chromatographic purification of tetramethylrhodamine-immune globulin conjugates and their use in the cellular localization of rabbit gamma-globulin polypeptide chains. J. Immunol. 95:230.
29. Minoyama, J., T. Ohnuma, and G. E. Moore. 1972. Rosette-forming human lymphoid cell lines. I. Establishment and evidence for origin of thymus-derived lymphocytes. J. Natl. Cancer Inst. 49:891.
30. Royston, I., R. W. Smith, D. N. Buell, E. Huang, and J. S. Pogano. 1974. Autologous human B and T lymphoblastoid cell lines. Nature (Lond.). 251:745.
31. Bôyum, A. 1968. Isolation of mononuclear cells and granulocytes from human blood: isolation of mononuclear cells by one centrifugation and of granulocytes by combining centrifugation and sedimentation at lg. Scand. J. Clin. Lab. Invest. 21(Suppl. 97):77.
32. Gutman, G. A., and I. L. Weissman. 1972. Lymphoid tissue architecture: experimental analysis of the origin and distribution of T-cells and B-cells. Immunology. 23:465.
33. Lobo, P. L., F. B. Westervelt, and D. A. Horwitz. 1975. Identification of two populations of immunoglobulin-bearing lymphocytes in man. J. Immunol. 114:116.
34. Winchester, R. J., S. M. Fu, T. Hoffman, and H. G. Kunkel. 1975. IgG on lymphocyte surfaces: technical problems and the significance of a third cell population. J. Immunol. 114:1210.
35. Aisenberg, A. C., K. J. Bloch, and J. C. Long. 1973. Cell-surface immunoglobulins in chronic lymphocytic leukemia and allied disorders. Am. J. Med. 55:184.
36. Brouet, J., G. Flandrin, and M. Seligmann. 1973. Indications of thymus-derived nature of the proliferating cells in six patients with Sézary’s syndrome. N. Engl. J. Med. 289:341.
37. Zucker-Franklin, D., J. W. Melton, III, and F. Quagliata. 1974. Ultrastructural, immunologic, and functional studies on Sézary cells: a neoplastic variant of thymus-derived (T) lymphocytes. Proc. Natl. Acad. Sci. U. S. A. 71:1877.
38. Wernet, P., T. Feizi, and H. G. Kunkel. 1972. Idiotypic determinants of immunoglobulin M detected on the surface of human lymphocytes by cytotoxicity assays. J. Exp. Med. 136:650.
39. Rudders, R. A., V. Yakulis, and P. Heller. 1973. Double myeloma: production of both IgG type lambda and IgA type lambda myeloma proteins by a single plasma cell line. Am. J. Med. 55:215.
40. Stevenson, G. T., and F. K. Stevenson. 1975. Antibody to a molecularly-defined antigen confined to a tumor cell surface. Nature (Lond.). 254:714.
41. Oriol, R., J. Huerta, J. P. Houvet, and P. Leacopoulos. 1974. Two myeloma globulins IgGl-k and IgGl-T from a single patient (Im). Immunology. 27:1081.
42. Morse, H. C., J. C. Pumphrey, M. Potter, and R. Asofsky. 1976. Murine plasma cells secreting more than one class of immunoglobulin heavy chain. I. Frequency of two or more m-components in ascitic fluids from 788 primary plasmacytomas. J. Immunol. 117:541.
43. Axelsson, U., and J. Hàllén. 1968. Review of fifty-four subjects with monoclonal gammopathy. Br. J. Haematol. 15:417.
44. Jaffe, E. S., E. M. Shevach, M. M. Frank, C. W. Berard, and I. Green. 1974. Nodular lymphoma - evidence for origin from follicular B lymphocytes. N. Engl. J. Med. 290:813.
45. Taylor, C. R. 1974. The nature of Reed-Sternberg cells and other malignant "reticulum" cells. Lancet. 2:802.
46. Garvin, A. J., S. S. Spicer, R. T. Parmley, and A. M. Munster. 1974. Immunohisto-chemical demonstration of IgG in Reed-Sternberg and other cells in Hodgkin’s disease. J. Exp. Med. 139:1077.
47. Warner, N. L. 1974. Membrane immunoglobulins and antigen receptors on B and T lymphocytes. Adv. Immunol. 19:67.
48. Braylan, R. C., and H. Rappaport. 1973. Tissue immunoglobulins in nodular lymphomas as compared with reactive follicular hyperplasia. Blood. 42:579.
49. Rappaport, H., and R. C. Braylan. 1975. Changing concepts in the classification of malignant neoplasms of the hematopoietic system. Int. Acad. Pathol. Mongr. 16:1.
50. Lennert, K., H. Stein, and E. Kaiserling. 1975. Cytological and functional criteria for the classification of malignant lymphoma. Br. J. Cancer. 31(Suppl. 2):29.
51. Lukes, R. J., and R. D. Collins. 1975. New approaches to the classification of the lymphomata. Br. J. Cancer. 31(Suppl. 2):1.
52. Dorfman, R. F. 1974. A newly proposed classification of the non-Hodgkin’s lymphomas. Lancet. 1:1295.
53. Dorfman, R. F. 1975. The non-Hodgkin’s lymphomas in the reticuloendothelial system. Int. Acad. Pathol. Monogr. 16:262-281.
54. Kim, H., and R. F. Dorfman. 1974. Morphological studies of 84 untreated patients subjected to laparotomy for the staging of non-Hodgkin’s lymphomas. Cancer. 33:657.