Resistance of germfree rats to indomethacin-induced intestinal lesions

Prostaglandins

Volumn 14, Issue 2, 1977, Pages 333-341

  Robert, André ^a   Asano, Tomoaki ^b  

^a PFIZER INC   (United States)

^b UNIVERSITY OF NOTRE DAME   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; INDOMETACIN; PROSTAGLANDIN E2 DERIVATIVE;

ADVERSE DRUG REACTION; DOSE RESPONSE; DRUG RESPONSE; ESCHERICHIA COLI; INTESTINE; INTESTINE ULCER; MICROORGANISM; ORAL DRUG ADMINISTRATION; PROSTAGLANDIN DEFICIENCY; RAT; THEORETICAL STUDY;

ANIMAL; ESCHERICHIA COLI; FEMALE; GERM-FREE LIFE; INDOMETHACIN; INTESTINAL DISEASES; INTESTINES; MALE; PERITONITIS; PROSTAGLANDINS E; RATS; RATS, INBRED STRAINS; SEX FACTORS; ULCER;

EID: 0017690751     PISSN: 00906980     EISSN: None     Source Type: Journal    
DOI: 10.1016/0090-6980(77)90178-2     Document Type: Article

References (9)

1. Small intestinal ulcers and intestinal flora in rats given indomethacin
2. Relationship of the enterohepatic cycle to ulcerogenesis in the rat small bowel with flufenamic acid
3. Effects of prostaglandins on the stomach and the intestine
4. An intestinal disease produced experimentally by a prostaglandin deficiency
5. Determination of germfree status
6. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
7. Bile acid metabolism in gnotobiotic animals
8. Fecal neutral steroids and bile acids from germfree rats
9. Indomethacin-induced intestinal lesions in the rat