Inhibition of Lactobacillus casei Thymidylate Synthetase by 5-Substituted 2′-Deoxyuridylates. Preliminary Quantitative Structure-Activity Relationship

Journal of Medicinal Chemistry

Volumn 20, Issue 11, 1977, Pages 1469-1473

  Wataya, Yusuke ^a   Santi, Daniel V ^a   Hansch, Corwin ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b POMONA COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYURIDINE; THYMIDYLATE SYNTHASE;

2' DEOXY 5 HALOURIDYLIC ACID; 5 HYDROXYMETHYLDEOXYURIDINE PHOSPHATE; 5 SUBSTITUTED 2' DEOXYURIDYLIC ACID; 5 TRIFLUOROMETHYL 2' DEOXYURIDYLIC ACID; DRUG COMPARISON; ENZYME INHIBITION; IN VITRO STUDY; LACTOBACILLUS CASEI; STRUCTURE ACTIVITY RELATION; THEORETICAL STUDY;

DEOXYURACIL NUCLEOTIDES; KINETICS; LACTOBACILLUS CASEI; METHYLTRANSFERASES; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, U.S. GOV'T, P.H.S.; THYMIDYLATE SYNTHASE;

EID: 0017672044     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00221a021     Document Type: Article

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