Autoimmunity to type II collagen: An experimental model of arthritis*

Journal of Experimental Medicine

Volumn 146, Issue 3, 1977, Pages 857-868

  Trentham, David E ^a,b   Townes, Alexander S ^a,b   Kang, Andrew H ^a,b  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN ANTIBODY; FREUND ADJUVANT;

ARTHRITIS; AUTOIMMUNE DISEASE; DIAGNOSIS; ETIOLOGY; INFLAMMATION; MICROORGANISM; MODEL; RAT; RHEUMATOID ARTHRITIS; THEORETICAL STUDY;

ANIMAL; ARTHRITIS; AUTOANTIBODIES; COLLAGEN; DISEASE MODELS, ANIMAL; FEMALE; FREUND'S ADJUVANT; INFLAMMATION; RATS; RATS, INBRED STRAINS; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; SYNOVIAL MEMBRANE;

EID: 0017657009     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.146.3.857     Document Type: Article

References (24)

1. Steffen, C, and R. Timpl. 1963. Antigenicity of collagen and its application in the serological investigation of rheumatoid arthritis sera. Int. Arch. Allergy Appl. Immunol. 22:333.
2. Steffen, C, F. Schuster, G. Tausch, R. Timpl, and I. Pecker. 1968. Weitere Untersuchungen über Kollagenantikörper bei Patienten mit primär chronischer Polyarthritis. Klin. Wochenschr. 46:976.
3. Steffen, C. 1970. Consideration of the pathogenesis of rheumatoid arthritis as collagen autoimmunity. Z. Immunitätsforsch. 139:219.
4. Michaeli, D., and H. H. Fudenberg. 1974. The incidence and antigenic specificity of antibodies against denatured human collagen in rheumatoid arthritis. Clin. Immunol. Immunopath. 2:153.
5. Cracchiolo, A., D. Michaeli, L. S. Goldberg, and H. H. Fudenberg. 1975. The occurrence of antibodies to collagen in synovial fluids. Clin. Immunol. Immunopath. 3:567.
6. Andriopoulos, N. A., J. C. Bennett, J. Mestecky, and E. J. Miller. 1975. The occurrence of antibodies against native human collagens in synovial fluids of patients with rheumatoid arthritis. Arthritis Rheum. 18:384.
7. Andriopoulos, N. A., J. Mestecky, E. J. Miller, and E. L. Bradley. 1976. Antibodies to native and denatured collagens in sera of patients with rheumatoid arthritis. Arthritis Rheum. 19:613.
8. Andriopoulos, N. A., J. Mestecky, G. P. Wright, and E. J. Miller. 1976. Characterization of antibodies to the native human collagens and to their component α chains in the sera and the joint fluids of patients with rheumatoid arthritis. Immunochemistry. 13:709.
9. Seraffini-Fracassini, A., and J. W. Smith, editors. 1974. Collagen. In The Structure and Biochemistry of Cartilage. Churchill Livingston, Edinburgh, Scotland. 29.
10. Traub, W., and K. A. Piez. 1971. The chemistry and structure of collagen. Adv. Protein Chem. 25:243.
11. 2α2. J. Immunol. 13:421.
12. Nowack, H., E. Hahn, and R. Timpl. 1975. Specificity of the antibody response in inbred mice to bovine type I and type II collagen. Immunology. 29:621.
13. Trelstad, R. L., A. H. Kang, S. Igarashi, and J. Gross. 1970. Isolation of two distinct collagens from chick cartilage. Biochemistry. 9:4993.
14. Seyer, J. M., E. T. Hutcheson, and A. H. Kang. 1976. Collagen polymorphism in idiopathic chronic pulmonary fibrosis. J. Clin. Invest. 57:1498.
15. Bitter, T., and H. M. Muir. 1962. A modified uronic acid carbazole reaction. Anal. Biochem. 4:330.
16. Wood, F. D., C. M. Pearson, and A. Tanaka. 1969. Capacity of mycobacterial wax D and its subtractions to induce adjuvant arthritis in rats. Int. Arch. Allergy Appl. Immunol. 35:456.
17. Hill, A., and G. J. R. Dagnall. 1975. Experimental polyarthritis in rats produced by Mycoplasma arthritidis. J. Comp. Pathol. 85:45.
18. Volkman, A., and F. M. Collins. 1973. Polyarthritis associated with Salmonella infection in rats. Infect. Immun. 8:814.
19. Steffen, C, and G. Wick. 1971. Delayed hypersensitivity reactions to collagen in rats with adjuvant-induced arthritis. Z. Immunitätsforsch. 141:169.
20. Trentham, D. E., and J. R. David. 1977. Cellular sensitivity to collagen in adjuvant arthritis. Clin. Res. 25:369. Abstr.
21. Stewart-Tull, D. E. S., T. Shimono, S. Kotani, M. Kato, Y. Ogawa, Y. Yamamura, T. Koga, and C. M. Pearson. 1975. The adjuvant activity of a non-toxic, water-soluble glycopeptide present in large quantities in the culture filtrate of Mycobacteria tuberculosis strain DT. Immunology. 29:1.
22. Hadler, N. M. 1976. A pathogenetic model for erosive synovitis: lessons from animal arthritides. Arthritis Rheum. 19:256.
23. Smith, J. A., J. G. R. Hurrell, and S. J. Leach. 1977. Conformational integrity of myoglobin after immunization with Freund’s adjuvant. J. Immunol. 118:226.
24. Rose, N. R. 1973. Self-recognition and autoimmunity. In Principles of Immunology. N. R. Rose, F. Milgrom, and C. J. van Oss, editors. Macmillan, Inc., New York. 217.