Improvement of Cis‐dichlorodiammineplatinum (NSC 119875): Therapeutic index in an animal model

Cancer

Volumn 39, Issue 4, 1977, Pages 1357-1361

  Cvitkovic, Esteban ^a   Spaulding, Joseph ^a   Bethune, Vlctor ^a   Martin, James ^a   Whitmore, Willet F ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; GLUCOSE; MANNITOL;

BLOOD; BONE MARROW TOXICITY; CANCER CHEMOTHERAPY; DOG; DRUG BLOOD LEVEL; DRUG URINE LEVEL; MODEL; OSMOTIC DIURESIS; PHARMACOKINETICS; THEORETICAL STUDY; THERAPEUTIC INDEX; URINE;

ANIMALS; BONE MARROW; CISPLATIN; DIURESIS; DOGS; INFUSIONS, PARENTERAL; INJECTIONS, INTRAVENOUS; KIDNEY; MANNITOL;

EID: 0017656335     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/1097-0142(197704)39:4<1357::AID-CNCR2820390402>3.0.CO;2-C     Document Type: Article

References (8)

1. Clinical and pharmacological studies with cis‐Diamminedichloroplatinum (II)
2. Acute toxicologic and pathologic effects of cis‐Diamminedichloroplatinum (NSE 119875) in the male rat
3. 195mPt
4. Antileukaemic and nephrotoxic properties of platinum compounds
5. C is‐Dichlorodiammineplatinum (II) (NSC 119875) preclinical toxicologic evaluation of intravenous injection in dogs, monkeys and mice
6. Mercury‐induced renal vascular shut‐down: Observations in experimental acute renal failure
7. 195mPt‐cis‐Dichlorodiam‐mineplatinum (II) in Man
8. 14C) ethylenediamine dichloride in the rat