Metabolic activation of the carcinogen 7,12-dimethylbenz[a]anthracene for DNA binding

Biochemical and Biophysical Research Communications

Volumn 76, Issue 4, 1977, Pages 1092-1098

  Moschel, R C ^a   Baird, W M ^b   Dipple, A ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b WISTAR INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN; DIMETHYLBENZ[A]ANTHRACENE; DNA;

3,4 DIHYDRO 3,4 DIHYDROXYBENZ[A]ANTHRACENE; 5,6 DIHYDRO 5,6 DIHYDROXY 7,12 DIMETHYLBENZ[A]ANTHRACENE; 7,12 DIMETHYLBENZ[A]ANTHRACENE H 3; 8,9,10,11 TETRAHYDRO 7,12 DIMETHYLBENZ[A]ANTHRACENE; 9,10 DIMETHYLANTHRACENE; CELL; CHROMATOGRAPHY; DRUG ACTIVATION; EMBRYO; IN VITRO STUDY; MOUSE; SPECTROMETRY; THEORETICAL STUDY;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMAL; BENZANTHRACENES; CELLS, CULTURED; CHEMISTRY; DEOXYRIBONUCLEASES; DNA; MICE; SPECTROMETRY, FLUORESCENCE; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0017654331     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/0006-291X(77)90968-8     Document Type: Article

References (16)

1. 42. Oxidation of carcinogenic hydrocarbons by osmium tetroxide
2. Structure and activity in chemical carcinogenesis. Comparison of the reactions of 7-bromomethylbenz[α]anthracene and 7-bromomethyl-12-methylbenz[α]anthracene with mouse skin deoxyribonucleic acid in vivo