Alteration of hepatic microsomal enzymes by griseofulvin treatment of mice

Biochemical Pharmacology

Volumn 26, Issue 12, 1977, Pages 1125-1130

  Denk, Helmut ^c   Eckerstorfer, Romana ^c   Talcott, Ronald E ^c   Schenkman, John B ^a,b  

^a YALE UNIVERSITY   (United States)

^b UNIVERSITY OF VIENNA   (Austria)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A DESATURASE; CYTOCHROME; CYTOCHROME P 450 ENZYME SYSTEM; CYTOCHROME P450; GRISEOFULVIN; HEME; LIPID; MIXED FUNCTION OXIDASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PROTEIN; AMINOPYRINE N DEMETHYLASE; CYTOCHROME B5; CYTOCHROME B5 REDUCTASE; ENZYME; LIPID PEROXIDE; OXIDOREDUCTASE; RADIOISOTOPE;

ANIMAL; ARTICLE; BODY WEIGHT; DRUG EFFECT; ENZYMOLOGY; IN VITRO STUDY; LIVER; LIVER MICROSOME; MALE; METABOLISM; MOUSE; ORGAN WEIGHT; TIME; DRUG METABOLISM; PHARMACOKINETICS; STEAROYL COENZYME A C 14; THEORETICAL STUDY;

ANIMAL; BODY WEIGHT; CYTOCHROME P-450 ENZYME SYSTEM; CYTOCHROMES; FATTY ACID DESATURASES; GRISEOFULVIN; HEME; IN VITRO; LIPIDS; LIVER; MALE; MICE; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; NAD; NADP; ORGAN WEIGHT; PROTEINS; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS;

EID: 0017622946     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(77)90055-7     Document Type: Article

References (32)

1. DISTURBANCE OF PORPHYRIN METABOLISM CAUSED BY GRISEOFULVIN IN MICE.
2. PROTOPORPHYRIN, CIRRHOSIS AND HEPATOMATA IN THE LIVERS OF MICE GIVEN GRISEOFULVIN.
3. Behavior of hepatic microsomal cytochromes after treatment of mice with drugs known to disturb porphyrin metabolism in liver
4. The Molar Light Absorption of Pyridine Ferroprotoporphrin (Pyridine Haemochromogen).
5. Apocytochrome P-450: reconstitution of functional cytochrome with hemin in vitro.