δ‐Aminolevulinic acid: Influences on synaptic GABA receptor binding may explain CNS symptoms of porphyria

Annals of Neurology

Volumn 2, Issue 4, 1977, Pages 340-342

  Müller, Walter E ^a   Snyder, Solomon H ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; AMINOLEVULINIC ACID; BARBITURIC ACID DERIVATIVE; DRUG RECEPTOR; MUSCIMOL; RADIOISOTOPE;

4 AMINOBUTYRIC ACID H 3; ACUTE INTERMITTENT PORPHYRIA; ANIMAL EXPERIMENT; BRAIN; CENTRAL NERVOUS SYSTEM; DRUG BINDING; ETIOLOGY; FROG; GLYCINE H 3; PATHOGENESIS; PORPHYRIA; RAT; SPINAL CORD; STRYCHNINE H 3; SYNAPTIC MEMBRANE;

AMINOLEVULINIC ACID; ANIMAL; ANURA; BINDING, COMPETITIVE; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; GAMMA-AMINOBUTYRIC ACID; GLYCINE; LEVULINIC ACIDS; MALE; PORPHYRIA; RANA CATESBEIANA; RATS; RECEPTORS, NEUROTRANSMITTER; SODIUM; SPINAL CORD; STRYCHNINE; SUPPORT, U.S. GOV'T, P.H.S.; SYNAPTOSOMES;

EID: 0017613802     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.410020415     Document Type: Article

References (19)

1. Delta‐aminolevulinic acid uptake by rabbit brain cerebral cortex
2. Repression of the overproduction of porphyrin precursors in acute intermittent porphyria by intravenous infusion of hematin
3. The hyperpolarization of spinal motoneurones by glycine and related amino acids
4. The acute porphyria attack: III. Acute porphyria: the precipitating and aggravating factors
5. Properties of γ‐aminobutyric acid (GABA) receptor binding in rat brain synaptic membranes
6. Influences of ions, enzymes and detergents on GABA receptor binding in synaptic membranes of rat brain
7. γ‐Aminobutyric acid (GABA) in human cerebrospinal fluid: radioreceptor assay
8. Measurement of GABA in human cerebrospinal fluid
9. The effect of certain barbiturates on the porphyria metabolism of rabbits
10. Acute intermittent porphyria
11. GABA uptake in rat central nervous system: comparison of uptake in slices and homogenates and the effects of some inhibitors
12. High affinity uptake systems for glycine, glutamic and aspartic acids in synaptosomes of rat central nervous system
13. The passage of δ‐aminolevulinic acid across the blood‐brain barrier of the rat: effect of ethanol
14. Presynaptic action of barbiturates in the frog spinal cord
15. The interaction of porphyrin precursors with GABA receptors in the isolated frog spinal cord
16. The psychiatric symptoms of porphyria
17. Acute intermittent porphyria: increased ALA‐synthetase activity during an acute attack
18. Pharmakologische und experimentalpsychologische Untersuchungen mit 2 Inhaltsstoffen des Fliegenpilzes (Amanita muscaria)
19. Strychnine binding in rat spinal cord membranes associated with the synaptic glycine receptor: cooperativity of glycine interactions