Effects on Rat Liver Acetaldehyde Dehydrogenases in Vitro and in Vivo by Coprine, the Disulfiram‐like Constituent of Coprinus atramentarius

Acta Pharmacologica et Toxicologica

Volumn 40, Issue 4, 1977, Pages 476-481

  Tottmar, O ^a,b   Lindberg, P ^a,b  

^a UPPSALA UNIVERSITY   (Sweden)

^b LUND INSTITUTE OF TECHNOLOGY   (Sweden)

Author keywords

acetaldehyde; aldehyde dehydrogenase; antabus; disulfiram; Ethanol metabolism; rats

Indexed keywords

ALCOHOL; ALDEHYDE DEHYDROGENASE; COPRINE; DISULFIRAM; LIVER ENZYME;

1 AMINOCYCLOPROPANOL; AMINOCYCLOPROPANOL; COPRINUS; COPRINUS ATRAMENTARIUS; DRUG COMPARISON; RAT; THEORETICAL STUDY;

ACETALDEHYDE; ALDEHYDE OXIDOREDUCTASES; ANIMAL; BASIDIOMYCOTA; CYCLOPROPANES; ETHANOL; FEMALE; GLUTAMINE; HYDROLYSIS; LIVER; RATS; TIME FACTORS;

EID: 0017600133     PISSN: 00016683     EISSN: 16000773     Source Type: Journal    
DOI: 10.1111/j.1600-0773.1977.tb02100.x     Document Type: Article

References (6)

1. Mechanism of the inhibition of aldehyde dehydrogenase in vivo by disulfiram and diethyldithiocarbamate
2. Isolation and structural studies of Coprine, the disulfiram‐like constituent of Coprinus atramentarius
3. The effect of disulfiram on the aldehyde dehydrogenase of sheep liver
4. Isolation and structure of Coprine, a novel physiologically active cyclopropanone derivative from Coprinus atramentarius and its synthesis via 1‐aminocyclopropanol
5. Disulfiram as a tool in the studies on the metabolism of acetaldehyde in rats