Isolation of toxic metabolites of phomopsis leptostromiformis responsible for lupinosis

Australian Journal of Biological Sciences

Volumn 30, Issue 4, 1977, Pages 269-278

  Culvenor, C C J ^a   Clarke, M ^a   Cockrum, P A ^a   Edgar, J A ^a   Frahn, J L ^a   Jago, M V ^a   Lanigan, G W ^a   Payne, A L ^a   Peterson, J E ^a   Smith, L W ^a   Beck, A B ^b   Hearnshaw, D S ^c   White, R R ^c  

^a CSIRO   (Australia)

^b CSIRO LAND AND WATER   (Australia)

^c DEPARTMENT OF AGRICULTURE AND FOOD WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

MYCOTOXIN; PLANT TOXIN; SOLVENT;

ANIMAL; ARTICLE; BIOASSAY; CELL CULTURE; CHEMISTRY; COUNTER CURRENT CHROMATOGRAPHY; DEUTEROMYCETES; ELECTROPHORESIS; IN VITRO STUDY; ISOLATION AND PURIFICATION; THIN LAYER CHROMATOGRAPHY;

ANIMAL; BIOLOGICAL ASSAY; CELLS, CULTURED; CHEMISTRY; CHROMATOGRAPHY, THIN LAYER; COUNTERCURRENT DISTRIBUTION; ELECTROPHORESIS; IN VITRO; MITOSPORIC FUNGI; MYCOTOXINS; PLANT POISONING; SOLVENTS;

EID: 0017524397     PISSN: 00049417     EISSN: None     Source Type: Journal    
DOI: 10.1071/BI9770269     Document Type: Article

References (17)

1. Anon, A., (1976). Toxic fungal metabolites. S. Afr. CSIR special report CHEM 250. p. 76.
2. Beno, M. A., and Christoph, G. G. (1976). X-ray crystal structure of cytochalasin H, a potent new [1 l]cytochalasan toxin.J. Chem. Soc. Chem. Commun.344-5.
3. Frahn, J. L. (1970). The use of Teflon film in quantitative analysis by enclosed-strip paper electrophoresis. The separation and determination of the valence states of iron. J.Chromatoar53 616-19.
4. Frahn, J. L., and Mills, J. A. (1959). Paper ionophoresis of carbohydrates. I. Procedures and results for four electrolytes.Aust. J. Chem.12, 65-89.
5. Frahn, J. L., and Mills, J. A. (1964). Paper ionophoresis of amino compounds. Formation of carbamates, and related reactions.Aust. J. Chem.17, 256-73.
6. Gardiner, M. R. (1976a). Lupinosis.Adv. Vet. Sci.11, 85-138.
7. Gardiner, M. R. (1976b). Liver cell abnormalities induced in mice by the fungal toxin causing lupinosis.J. Pathol. Bacteriol.94, 452-5.
8. Gardiner, M. R., and Petterson, D. S. (1972). Pathogenesis of mouse lupinosis induced by a fungus(Cytosporaspp.) growing on dead lupins.J. Comp. Pathol.82, 5-13.
9. Kung, H.-C., Chipley, J. R., Latshaw, J. D., and Kerr, K. M. (1976). Mycotoxicosis in chicks produced by toxins fromPhomopsissp. orDiaporthephaseolorumvar.sojae. Avian Dis.20, 504-18.
10. Lowry, O. H., Rosebrough, N. J., Lewis Farr, A., and Randall, R. J. (1951). Protein measurement with the Folin phenol reagent.J. Biol. Chem.193, 265-75.
11. Marasas, W. F. O. (1974).Phomopsis leptostromiformis.In ‘Mycotoxins’. (Ed. I. F. H. Purchase.) pp. 111-27. (Elsevier: Amsterdam.)
12. Patwardhan, S. A., Pandey, R. C., Sukh Dev, and Pendse, G. S. (1974). Toxic cytochalasins ofPhomopsis paspali, a pathogen of kodo millet.Phytochemistry13, 1985-8.
13. Petterson, D. S., and Coackley, W. (1973). Changes in cell cultures produced by toxic lupin extracts.Aust. J. Exp. Biol. Med. Sci.51, 513-20.
14. Petterson, D. S., and Parr, W. H. (1970). Investigations into a hepatotoxin in lupin roughage.Res. Vet. Sci.11, 282-5.
15. Rothweiler, W., and Tamm, Ch. (1970). Isolierung und struktur der antibiotica phomin und 5-dehydrophomin.Helv. Chim. Acta53, 696-724.
16. van Warmelo, K. T., Marasas, W. F. O., Adelaar, T. F., Kellerman, T. S., van Rensburg, I. B. J., and Minne, J. A. (1970). Experimental evidence that lupinosis of sheep is a mycotoxicosis caused by the fungus, Phomopsis leptostromiformis(Kuhn) Bubak.J. S. Afr. Vet. Med. Assoc.41, 235-47.
17. Wells, J. M., Cutler, H. G., and Cole, R. J. (1976). Toxicity and plant growth regulator effects of cytochalasin H isolated fromPhomopsissp.Can. J. Microbiol.22, 1137-43.