The occurrence of cytochrome P-450 and aryl hydrocarbon hydroxylase activity in drosophila melanogaster microsomes, and the importance of this metabolizing capacity for the screening of carcinogenic and mutagenic properties of foreign compounds

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 44, Issue 2, 1977, Pages 257-267

  Baars, A J ^a,b   Zijlstra, J A ^a,b   Vogel, E ^a,b   Breimer, D D ^a,b  

^a LEIDEN UNIVERSITY   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BENZO[A]PYRENE; CARCINOGEN; CHEMICAL MUTAGEN; CYTOCHROME P450; ENZYME; HYDROXYBENZO[A]PYRENE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNSPECIFIC MONOOXYGENASE;

CARCINOGENESIS; DROSOPHILA; DROSOPHILA MELANOGASTER; DRUG METABOLISM; IN VITRO STUDY; MICROORGANISM; MICROSOME; MUTAGENESIS; PHARMACOKINETICS;

ANIMAL; ARYL HYDROCARBON HYDROXYLASES; CARCINOGENS; CYTOCHROME P-450 ENZYME SYSTEM; DROSOPHILA MELANOGASTER; DRUG EVALUATION, PRECLINICAL; GENETIC TECHNIQUES; MICROSOMES; MUTAGENS;

EID: 0017404870     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/0027-5107(77)90083-5     Document Type: Article

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