A New Alkaloid Am-2282 Of Streptomyces Origin Taxonomy, Fermentation, Isolation And Preliminary Characterization

The Journal of Antibiotics

Volumn 30, Issue 4, 1977, Pages 275-282

  Omura, Satoshi ^a   Iwai, Yuzuru ^a   Hirano, Atsushi ^a   Nakagawa, Akira ^a   Awaya, Juichi ^a   Tsuchiya, Hisae ^a   Takahashi, Yoko ^a   Masuma, Rokurou ^a  

^a KITASATO INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID; STAUROSPORINE;

BLOOD PRESSURE; DRUG ANALYSIS; DRUG INDUSTRY; DRUG ISOLATION; DRUG SCREENING; DRUG TOXICITY; FUNGUS; INFRARED SPECTROMETRY; INTRAPERITONEAL DRUG ADMINISTRATION; MICROORGANISM; MOUSE; PROTON NUCLEAR MAGNETIC RESONANCE; STREPTOMYCES; STREPTOMYCETACEAE; TAXONOMY; THEORETICAL STUDY; THIN LAYER CHROMATOGRAPHY; ULTRAVIOLET SPECTROPHOTOMETRY; YEAST;

ALKALOIDS; ANIMALS; CHEMISTRY; FERMENTATION; LETHAL DOSE 50; MICE; MICROBIAL SENSITIVITY TESTS; STREPTOMYCES; TIME FACTORS;

EID: 0017395981     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.7164/antibiotics.30.275     Document Type: Article

References (18)

1. Omura, s.; H. Tanaka, J. Awaya, Y. Nari-MATSU, Y. Konda & T. Hata: Pyrindicin, a new alkaloid from a Streptomyces strain. Taxonomy, fermentation, isolation and biological activity. Agr. Biol. Chem. 38: 899~906, 1974
2. Onda, M.; Y. Konda, Y. Narimatsu, H. Tanaka, J. Awaya & S. Omura: Alkaloids from Strepto-tnyces sp. NA-337A. Chem. Pharm. Bull. 22: 2916~2920, 1974
3. Omura, S.; Y. Suzuki, C. Kitao, Y. Takahashi & Y. Konda: Isolation of a new sulfur-containing basic substance from a Thermoactinomyces species. J. Antibiotics 28: 609~610, 1975
4. Waksman, s. a. : The actinomycetes. Vol. II. The Williams & Wilkins Co., Baltimore, 1961
5. Shirling, E. B. & D. Gottlieb: Methods for characterization of Streplomyces species. Int. J. Syst. Bacteriol. 16: 313~340, 1966
6. Container Corporation of America; Color Harmony Manual.
7. Buchanan, R. E. & N.E. Gibbons: Bergey's Manual of Determinative Bacteriology. 8th ed. The Williams & Wilkins Co., Baltimore, 1974
8. Pridham, T. G.; C. W. Hesseltine & R. G. Benedict: A guide for the classification of Streptomyces according to selected groups: Placement of strains in morphological sections. Appl. Microbiol. 6: 52~79, 1958
9. Waksman, S. A.: The Actinomycetes. Vol. II. p. 295, The Williams & Wilkins Co., Baltimore, 1961
10. Reusser, F. : Enzymatic modification of bovine growth hormone by proteolytic Streplomycete cell extracts. U. S. Patent 3, 317, 400, 1967
11. SfflBATA, M.; T. Hasegaw^a & E. Higashide: Tolypomycin, a new antibiotic. I. Streptomyces toly-pophorus nov. sp., a new antibiotic, tolypomycin-producer. J. Antibiotics 24: 810~815, 1971
12. Kanedo, Y. ; T. Terashima & Y. Kuroda: A new alkaloid produced by Streptomyces. Agr. Biol. Chem. 32:783-785, 1968
13. TERASfflMA, T.; Y. Kuroda & Y. Kanedo: Studies on a new alkaloid of Streptomyces. Structure of nigrifactin. Tetrahedron Letters 1969: 2532~2537, 1969
14. Umezawa, H. ; T. Tasaki & S. Fukuyama : An antiviral substance, avikoviromycin, produced by Streptomyces species. J. Antibiotics, Ser. A 5: 469~476, 1952
15. Gurevich, A. I.; M. N. Kolosov, V. G. Korobko & V. V. Onoprienko: The structure of avikoviromycin. Tetrahedron Letters 1968: 2209~2212, 1968
16. Konishi, M.; M. Kimeda, H. Tsukiura, H. Yamamoto, T. Hoshiya, T. Miyaki, K. Fujisawa, H. Koshi-yama & H. Kawaguchi: Oxamicetin, a new antibiotic of bacterial origin. I. Production, isolation and properties. J. Antibiotics 26: 752~764, 1973
17. Maeda, K.; H. Kosaka, Y. Okami & H. Umezawa : A new antibiotic, pyridomycin. J. Antibiotics, Ser. A 6: 140, 1953
18. Ogawara, H.; K. Maeda, G. Koyama, H. Naganawa & H. Umezawa: The chemistry of pyridomycin. Chem. Pharm. Bull. 16: 679~687, 1968